María P. Sepulcre

Centro de Investigación Biomédica en Red — Spain

Immunology and Microbiology · Life Sciences

28h-index2.5kcitations48works0.02yr avg
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Research Topics

Aquaculture disease management and microbiota(33), Immune Response and Inflammation(19), interferon and immune responses(13), Invertebrate Immune Response Mechanisms(7), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(6)

Publications48 total

TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome
EMBO Molecular Medicine·2026Open Access
Inhibition of NLRP1 Inflammasome Activation by Tyrosine Kinase Inhibitors Restores Erythropoiesis in Diamond-Blackfan Anemia Syndrome
2025Open Access
Evolution of LPS recognition and signaling: The bony fish perspective
Developmental & Comparative Immunology·2023· 27 citedOpen Access
Peroxisome proliferator-activated receptors alpha and beta mediate the anti-inflammatory effects of the cyclopentenone prostaglandin 15-deoxy-Δ12,14-PGJ2 in fish granulocytes
Developmental & Comparative Immunology·2022· 1 citedOpen Access
The molecular, functional and phylogenetic characterization of PGE2 receptors reveals their different roles in the immune response of the teleost fish gilthead seabream (Sparus aurata L.)
Developmental & Comparative Immunology·2020Open Access
Comunicaciones Póster.-Effects of 17α-ethinylestradiol in the immune system of the gilthead seabream (Sparus aurata L.) through mast cells
II Jornadas Doctorales de la Universidad de Murcia·2020
Aluminum is a powerful adjuvant in teleost fish despite failing to induce interleukin-1β release
Developmental & Comparative Immunology·2018· 12 cited
Identification of an interferon-stimulated gene, isg15 , involved in host immune defense against viral infections in gilthead seabream ( Sparus aurata L.)
Fish & Shellfish Immunology·2017· 15 citedOpen Access
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
Nature Communications·2016· 124 citedOpen Access
Prostaglandin E2 promotes M2 polarization of macrophages via a cAMP/CREB signaling pathway and deactivates granulocytes in teleost fish
Fish & Shellfish Immunology·2016· 34 cited
Editorial: Fish neutrophils meet proresolving eicosanoids
Journal of Leukocyte Biology·2016· 2 citedOpen Access
The role of prostaglandins in the regulation of fish immunity
Molecular Immunology·2015· 72 cited
Professional phagocytic granulocyte-derived PGD2 regulates the resolution of inflammation in fish
Developmental & Comparative Immunology·2015· 20 citedOpen Access
Md1 and Rp105 regulate innate immunity and viral resistance in zebrafish
Developmental & Comparative Immunology·2015· 23 citedOpen Access
Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress–Induced Inflammation
PLoS Biology·2014· 72 citedOpen Access
Toll-like receptor 22 of gilthead seabream, Sparus aurata: Molecular cloning, expression profiles and post-transcriptional regulation
Developmental & Comparative Immunology·2013· 35 cited
Identification and functional characterization of a new IL-1 family member, IL-1Fm2, in most evolutionarily advanced fish
Innate Immunity·2013· 16 citedOpen Access
Role for prostaglandins in the regulation of inflammation in gilthead seabream (Sparus aurata)
Fish & Shellfish Immunology·2013
Molecular cloning, phylogenetic analysis and functional characterization of soluble Toll-like receptor 5 in gilthead seabream, Sparus aurata
Fish & Shellfish Immunology·2013· 43 cited
Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β
Innate Immunity·2012· 92 citedOpen Access
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Frequent Co-authors

Víctoriano Mulero(43), José Meseguer(25), Azucena López‐Muñoz(13), Francisco J. Roca(9), Victoria Gómez-Abellán(7), Diana García‐Moreno(7), Pablo Pelegrı́n(6), Sylwia D. Tyrkalska(6), Marta Arizcún(6), María L. Cayuela(5), Iván Mulero(5), Alfonsa García‐Ayala(5), Gloria López‐Castejón(5), Sergio Candel(5), Diego Angosto-Bazarra(5), Francisca Alcaraz‐Pérez(4), Elena Sarropoulou(4), António Figueras(4), A. Garcı́a-Alcázar(4), Jana Montero(4)