Howard A. Rockman

Duke Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

79h-index23.4kcitations273works14.62yr avg
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Research Topics

Receptor Mechanisms and Signaling(135), Cardiac electrophysiology and arrhythmias(44), Cardiomyopathy and Myosin Studies(42), Neuropeptides and Animal Physiology(36), Ion channel regulation and function(29)

Publications273 total

Cardiomyocyte β-arrestins mediate inflammation and cGAS-STING activation in CVB3 viral myocarditis
American Journal of Physiology-Heart and Circulatory Physiology·2026· 1 citedOpen Access
Amara Yad Image: 2-Chamber View of the Left Heart—Medial Segment
Journal of the American College of Cardiology·2025
A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia
Journal of Clinical Investigation·2025Open Access
Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation
JACC. Clinical electrophysiology·2025· 2 citedOpen Access
Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation
2025Open Access
Small-molecule modulation of β-arrestins
2024· 3 citedOpen Access
USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality
American Journal of Physiology-Heart and Circulatory Physiology·2024· 4 citedOpen Access
SNORD3A: a new possible circulating biomarker of human heart failure
European Heart Journal·2024· 1 cited
Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways
Science Signaling·2024· 11 citedOpen Access
Engineering and Characterization of a Long-Half-Life Relaxin Receptor RXFP1 Agonist
Molecular Pharmaceutics·2024· 6 citedOpen Access
G Protein-Coupled Receptors: A Century of Research and Discovery
Circulation Research·2024· 121 citedOpen Access
Antibodies expand the scope of angiotensin receptor pharmacology
Nature Chemical Biology·2024· 32 citedOpen Access
G protein–coupled receptors: from radioligand binding to cellular signaling
Journal of Clinical Investigation·2024· 9 citedOpen Access
How carvedilol does not activate β2-adrenoceptors
Nature Communications·2023· 11 citedOpen Access
Abstract 16000: β-arrestins Mediate Cardiac Infiltration of Cytotoxic CD8+ T Cells and Macrophages in Acute CVB3 Viral Myocarditis
Circulation·2023
Abstract P2154: A Novel Allosteric Modulator Of The β <sub>1</sub> AR Identified By DNA-encoded Small Molecule Library Screening Demonstrates Unique Pharmacology And Function
Circulation Research·2023
B-arrestin deletion abrogates the innate immune response in murine CVB3 myocarditis
Physiology·2023
Pathophysiology and pharmacology of G protein-coupled receptors in the heart
Cardiovascular Research·2022· 26 citedOpen Access
G protein-coupled receptor signaling: transducers and effectors
American Journal of Physiology-Cell Physiology·2022· 80 citedOpen Access
Engineering and characterization of a long half-life relaxin receptor RXFP1 agonist
2022· 3 citedOpen Access
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Frequent Co-authors

Robert J. Lefkowitz(17), Walter J. Koch(15), Lan Mao(10), John Ross(6), Kenneth R. Chien(6), Richard A. Bond(5), Sathyamangla V. Naga Prasad(5), Carmelo A. Milano(4), John Hunter(4), Jonathan D. Violin(4), Marc G. Caron(4), Lee F. Allen(3), Dong-Ju Choi(3), Louis M. Luttrell(3), Juhsien Chen(3), Giovanni Esposito(3), Thomas M. Coffman(3), Erin J. Whalen(3), Jonathan S. Stamler(3), Natasha C. Salazar(3)