Erin J. Whalen

Novo Nordisk (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index6.4kcitations54works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Receptor Mechanisms and Signaling(34), Neuropeptides and Animal Physiology(24), Nitric Oxide and Endothelin Effects(15), Heart Rate Variability and Autonomic Control(7), Neuroscience of respiration and sleep(6)

Publications54 total

The central fibroblast growth factor receptor/beta klotho system: Comprehensive mapping in <scp><i>Mus musculus</i></scp> and comparisons to nonhuman primate and human samples using an automated in situ hybridization platform
The Journal of Comparative Neurology·2019· 53 citedOpen Access
Small-molecule WNK inhibition regulates cardiovascular and renal function
Nature Chemical Biology·2016· 162 citedOpen Access
Hemodynamic responses elicited by systemic injections of isotonic and hypertonic saline in hemorrhaged rats
Microvascular Research·2013· 4 citedOpen Access
Erythrocyte plasma membrane–bound ERK1/2 activation promotes ICAM-4–mediated sickle red cell adhesion to endothelium
Blood·2011· 64 citedOpen Access
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
Nature·2011· 410 cited
Cardiorenal Actions of TRV120027, a Novel ß-Arrestin–Biased Ligand at the Angiotensin II Type I Receptor, in Healthy and Heart Failure Canines
Circulation Heart Failure·2011· 162 citedOpen Access
Application of an Experimentally Flexible Label-Free Quantitative Phosphoproteomics Strategy to Characterize Signaling Pathways within Human Red Blood Cell Membranes
2011
Therapeutic potential of β-arrestin- and G protein-biased agonists
Trends in Molecular Medicine·2010· 502 cited
Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance
Journal of Pharmacology and Experimental Therapeutics·2010· 362 cited
Cardiorenal Actions of TRV120027, a Novel, β-Arrestin-Biased Ligand at the Angiotensin II Type I Receptor, in Healthy and Heart Failure Canines: A Novel Therapeutic Strategy for Acute Heart Failure
Journal of Cardiac Failure·2010· 4 citedOpen Access
TRV120027, a β-Arrestin Biased Ligand at the Angiotensin II Type 1 Receptor, Produces Unique Pharmacology and Is a Novel Potential Therapy for Heart Failure
Journal of Cardiac Failure·2010· 2 cited
Oxygen-Regulated β <sub>2</sub> -Adrenergic Receptor Hydroxylation by EGLN3 and Ubiquitylation by pVHL
Science Signaling·2009· 151 citedOpen Access
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
Proceedings of the National Academy of Sciences·2009· 268 citedOpen Access
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
Journal of Clinical Investigation·2009· 231 citedOpen Access
β-Blockers alprenolol and carvedilol stimulate β-arrestin-mediated EGFR transactivation
Proceedings of the National Academy of Sciences·2008· 273 citedOpen Access
S-Nitrosylation of β-Arrestin Regulates β-Adrenergic Receptor Trafficking
Molecular Cell·2008· 179 citedOpen Access
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
Proceedings of the National Academy of Sciences·2008· 231 citedOpen Access
β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor
Journal of Biological Chemistry·2008· 50 citedOpen Access
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
Science·2008· 268 citedOpen Access
β-Arrestin-mediated Signaling Regulates Protein Synthesis
Journal of Biological Chemistry·2008· 91 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Robert J. Lefkowitz(20), Alan Kim Johnson(16), Stephen J. Lewis(16), Jonathan D. Violin(12), Scott M. DeWire(6), Seungkirl Ahn(5), Sudha K. Shenoy(5), Terry G. Beltz(5), Michael W. Lark(4), Jonathan S. Stamler(4), James W. Wisler(3), Matthew T. Drake(3), Jeffrey J. Kovacs(3), Kunhong Xiao(3), Howard A. Rockman(3), Rahima Zennadi(3), Marilyn J. Telen(3), Sudarshan Rajagopal(2), Christopher M. Lam(2), Dennis S. Yamashita(2)