U. Holwerda

Amsterdam Neuroscience — Netherlands

Medicine · Health Sciences

10h-index676citations13works0.02yr avg
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Research Topics

Colorectal Cancer Treatments and Studies(6), Metabolism and Genetic Disorders(4), Gastric Cancer Management and Outcomes(3), Genetic factors in colorectal cancer(3), Metal complexes synthesis and properties(2)

Publications13 total

Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis
JIMD Reports·2017· 5 citedOpen Access
A pilot study to estimate incidence of guanidinoacetate methyltransferase deficiency in newborns by direct sequencing of the GAMT gene
Gene·2015· 29 cited
A Non‐Radioactive Sensitive Assay to Measure 5‐Fluorouracil Incorporation into DNA of Solid Tumors
ChemInform·2005· 2 cited
A Non‐Radioactive Sensitive Assay to Measure 5‐Fluorouracil Incorporation into DNA of Solid Tumors
Nucleosides Nucleotides & Nucleic Acids·2004· 9 citedOpen Access
5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
Annals of Oncology·2004· 257 citedOpen Access
The Effect of Food on the Pharmacokinetics of S-1 after Single Oral Administration to Patients with Solid Tumors
Clinical Cancer Research·2004· 18 citedOpen Access
Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors
Cancer Chemotherapy and Pharmacology·2003· 52 cited
Quantitative analysis of urinary acylglycines for the diagnosis of β-oxidation defects using GC-NCI-MS
Journal of Pharmaceutical and Biomedical Analysis·2000· 47 citedOpen Access
Simultaneous analysis of plasma free fatty acids and their 3-hydroxy analogs in fatty acid β-oxidation disorders
Clinical Chemistry·1998· 99 citedOpen Access
Quantification of 5-Fluorouracil Incorporation into RNA of Human and Murine Tumors as Measured with a Sensitive Gas Chromatography-Mass Spectrometry Assay
Analytical Biochemistry·1995· 25 cited
The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278
Cancer Chemotherapy and Pharmacology·1992· 27 cited
Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse.
PubMed·1992· 66 cited
The chemical reactivity of the modulating agent WR2721 (ethiofos) and its main metabolites with the antitumor agents cisplatin and carboplatin
Biochemical Pharmacology·1991· 40 cited

Frequent Co-authors

Paul Noordhuis(6), Godefridus J. Peters(6), Herbert M. Pinedo(5), C.L. van der Wilt(3), M. Treskes(3), Kees Smid(2), Isabel Tavares de Almeida(2), Jan H. Schornagel(2), Daphne Voorn(2), Giuseppe Giaccone(2), P. Fumoleau(2), W. J. F. van der Vijgh(2), Gajja S. Salomons(2), Jan van Laar(2), C.J. van Groeningen(1), Sybren L. Meijer(1), Catarina G. Costa(1), L. Dorland(1), Bwee Tien Poll‐The(1), Cornelis Jakobs(1)