Christopher C. Goodnow

The University of Sydney — Australia

Immunology and Microbiology · Life Sciences

104h-index44.4kcitations419works3.82yr avg
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Research Topics

T-cell and B-cell Immunology(218), Immune Cell Function and Interaction(189), Immunotherapy and Immune Responses(67), Monoclonal and Polyclonal Antibodies Research(57), Immunodeficiency and Autoimmune Disorders(57)

Publications418 total

Framework-mediated binding of foreign and self-glycans by IGHV4–34 antibodies
Frontiers in Immunology·2026Open Access
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
Nature Immunology·2026Open Access
Proteotranscriptomic Dissection of Breast Cancer T Cell States Identifies CD103+ Tfh-derived Cytotoxic Cells Linked to Immunotherapy Response
2026Open Access
Humoral epitope dominance and immune imprinting by <scp>SARS</scp> ‐ <scp>CoV</scp> ‐1 and <scp>SARS</scp> ‐ <scp>CoV</scp> ‐2 vaccines
Immunology and Cell Biology·2026Open Access
Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Reply to Bousdar et al.: Common inherited loss-of-function mutations in the innate sensor <i>NOD2</i> contribute to exceptional immune response to cancer immunotherapy
Proceedings of the National Academy of Sciences·2025Open Access
Overactive STAT3 Dysregulates BCR Signalling and Drives Accumulation and Autoreactivity of Disease-Associated CD21low B Cells
Journal of Human Immunity·2025Open Access
A transcriptomic signature of self-reactivity in the germinal center 2203
The Journal of Immunology·2025Open Access
Detecting Somatic Mutations in Rare Clones using Single Cell Multi-Omics
2025Open Access
Refractory coeliac disease or something else?
Pathology·2025
Lymphoma driver mutations at the root of somatic evolution of nerve-damaging autoantibodies in myelin associated glycoprotein neuropathy
Journal of Autoimmunity·2025Open Access
Common inherited loss-of-function mutations in the innate sensor NOD2 contribute to exceptional immune response to cancer immunotherapy
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Essential cell-intrinsic requirement for GMDS in T cell development
Frontiers in Immunology·2025Open Access
Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease
Science Translational Medicine·2025· 6 cited
Can autoimmune disease be cured by deep CD19+ cell depletion?
The Journal of Immunology·2025· 7 citedOpen Access
A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease
Immunity·2025· 11 citedOpen Access
Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies
Proceedings of the National Academy of Sciences·2025· 5 citedOpen Access
Germline mutations in a G protein identify signaling cross-talk in T cells
Science·2024· 19 citedOpen Access
POS0883 EVIDENCE FOR SOMATIC MUTATION IN LYMPHOMA DRIVER GENES AT THE ROOT OF CLONAL EVOLUTION OF PATHOGENIC AUTOANTIBODIES IN MAG NEUROPATHY
Annals of the Rheumatic Diseases·2024
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
Immunity·2024· 23 citedOpen Access
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Frequent Co-authors

Carola G. Vinuesa(9), Jason G. Cyster(9), Robert Brink(6), James I. Healy(5), Richard J. Cornall(5), Michael P. Cooke(5), Anselm Enders(5), Antony Basten(4), Matthew Cook(4), Suzanne B. Hartley(4), Wyne P. Lee(3), Edward M. Bertram(3), Vishva M. Dixit(3), Ricardo E. Dolmetsch(3), Richard S. Lewis(3), J. Crosbie(3), Belinda Whittle(3), Teresa Lambe(3), Adrian Liston(3), Sylvie Lesage(3)