Dominick J. Laddy

International AIDS Vaccine Initiative — United States

Medicine · Health Sciences

24h-index2.5kcitations34works30.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(18), Immune responses and vaccinations(10), Immunodeficiency and Autoimmune Disorders(7), Immune Response and Inflammation(6), Immune Cell Function and Interaction(6)

Publications33 total

Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
Science·2025· 30 citedOpen Access
The quest for vaccine-induced immune correlates of protection against tuberculosis
Vaccine Insights·2022· 33 citedOpen Access
MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies
npj Vaccines·2021· 47 citedOpen Access
The TB vaccine development pathway – An innovative approach to accelerating global TB vaccine development
Tuberculosis·2020· 13 citedOpen Access
Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques
npj Vaccines·2020· 22 citedOpen Access
Prevention of tuberculosis in macaques after intravenous BCG immunization
Nature·2020· 584 citedOpen Access
Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques
npj Vaccines·2019· 70 citedOpen Access
Intravenous Bacille Calmette-Guerin provides protection across a dose spectrum in a Rhesus macaque model of tuberculosis
The Journal of Immunology·2019
Comparison of pellicle and shake flask-grown BCG strains by quality control assays and protection studies
Tuberculosis·2018· 16 cited
Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine
Nature Medicine·2018· 263 citedOpen Access
Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design
Infection and Immunity·2017· 33 citedOpen Access
Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis
PLoS ONE·2016· 63 citedOpen Access
Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
mBio·2016· 167 citedOpen Access
Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype
2016· 5 citedOpen Access
Ultra low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques
Tuberculosis·2015· 63 citedOpen Access
Nuclear imaging: A powerful novel approach for tuberculosis
Nuclear Medicine and Biology·2014· 30 citedOpen Access
Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG
Human Vaccines & Immunotherapeutics·2014· 25 citedOpen Access
Efficacy of a prime/boost regimen including BCG and recombinant protein in an HN878 challenge of C57BL/6 mice (P4296)
The Journal of Immunology·2013
Nonclinical Development of BCG Replacement Vaccine Candidates
Vaccines·2013· 35 citedOpen Access
Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets
Vaccine·2011· 36 cited
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Frequent Co-authors

David B. Weiner(14), Jian Yan(6), Patricia A. Darrah(5), Robert A. Seder(5), Thomas G. Evans(5), Kar Muthumani(5), Ann Williams(5), Aurelio Bonavia(4), Mario Roederer(4), Senthil G. Sundaram(4), Christopher Chung(4), Amir Sada Khan(4), Pauline Maiello(3), Joshua A. Hackney(3), Charles A. Scanga(3), JoAnne L. Flynn(3), Ling Wu(3), Michele A. Kutzler(3), Darwyn Kobasa(3), Ruxandra Draghia‐Akli(3)