Lee L. Eckhardt

University of Wisconsin–Madison — United States

Medicine · Health Sciences

32h-index6.8kcitations129works1.62yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(72), Ion channel regulation and function(37), Cardiac Arrhythmias and Treatments(26), Cardiac pacing and defibrillation studies(18), Cardiomyopathy and Myosin Studies(17)

Publications129 total

Loss-of-Function Mutation RyR2-A4860G Confers an Arrhythmia Phenotype in Mice Inconsistent With Calcium Release Deficiency Syndrome
Circulation Arrhythmia and Electrophysiology·2025Open Access
Large-scale functional assessment of variants of the potassium channel Kir2.1: Clinical and comparative insights
Journal of Biological Chemistry·2025Open Access
Addition of Metronidazole to Cefazolin for Surgical Site Injection Prophylaxis in Hysterectomy: A Systematic Review and Meta-Analysis
Journal of Minimally Invasive Gynecology·2025
High-Sensitivity Top-Down Proteomics Reveals Enhanced Maturation of Micropatterned Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Journal of Proteome Research·2025· 2 citedOpen Access
The role of iPSC research for insight into inherited arrhythmia conditions
Heart Rhythm·2025· 2 cited
hiPSC-derived cardiac fibroblasts dynamically enhance the mechanical function of hiPSC-derived cardiomyocytes on an engineered substrate
Frontiers in Bioengineering and Biotechnology·2025· 5 citedOpen Access
High-Sensitivity Top-Down Proteomics Reveals Enhanced Maturation of Micropatterned Induced Pluripotent Stem Cell-Derived Cardiomyocytes
2025Open Access
Atomic-level investigation of KCNJ2 mutations associated with ventricular arrhythmic syndrome phenotypes
Scientific Reports·2025· 2 citedOpen Access
PO-05-111 MOLECULAR MODELING AND LIVE-CELL BRET ANALYSIS REVEAL THE IMPACT OF KCNJ2 MUTATIONS ON PIP2 BINDING AND KIR2.1 CHANNEL FUNCTION
Heart Rhythm·2025Open Access
PO-02-076 OMNIPOLAR MAPPING, BOTH OMNIPOLAR VOLTAGE AND WAVESPEED, IS SENSITIVE TO MAPPING IN ATRIAL FIBRILLATION VERSUS SINUS RHYTHM
Heart Rhythm·2025
MANAGEMENT STRATEGY AND CARDIAC DEVICE CONSIDERATIONS IN A YOUNG PATIENT WITH J WAVE SYNDROME
Journal of the American College of Cardiology·2025Open Access
A PAS-targeting hERG1 activator reduces arrhythmic events in Jervell and Lange-Nielsen syndrome patient-derived hiPSC-CMs
JCI Insight·2025· 4 citedOpen Access
The impact of common and rare genetic variants on bradyarrhythmia development
Nature Genetics·2025· 13 citedOpen Access
Atomic-Level Investigation of <i>KCNJ2</i> Mutations Associated with Ventricular Arrhythmic Syndrome Phenotypes
2024· 1 citedOpen Access
Modeling Idiopathic Ventricular Fibrillation Using iPSC Cardiomyocytes and Computational Approaches
JACC. Clinical electrophysiology·2024· 4 citedOpen Access
Dynamic role of hormones on Brugada syndrome phenotype
HeartRhythm Case Reports·2024Open Access
Abstract Mo071: Engineered Platform to Uncover Cellular Cross-Talk and Arrhythmogenesis in Idiopathic Ventricular Fibrillation (IVF)
Circulation Research·2024
Abstract Mo086: Functional impact of phosphorylation-site mutations on PKA response of Kir2.1
Circulation Research·2024
Arrhythmia Research at a Tipping Point: The Need for Disruptive Science and Technology
Circulation Arrhythmia and Electrophysiology·2024Open Access
Top stories on the study of inherited arrhythmias using iPSCs
Heart Rhythm·2024Open Access
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Frequent Co-authors

Craig T. January(11), Jonathan C. Makielski(9), Timothy J. Kamp(9), Andrew D. Krahn(8), Mina K. Chung(7), Elizabeth S. Kaufman(7), Corey L. Anderson(7), Ravi Vaidyanathan(7), Arthur A.M. Wilde(7), Kate M. Orland(7), José A. Joglar(5), Emelia J. Benjamin(5), Rakesh Gopinathannair(5), Peter A. Noseworthy(5), Miguel A. Leal(5), Dan M. Roden(5), Louise Reilly(5), Marco Pérez(4), Andrea M. Russo(4), T. Jared Bunch(4)