Julie Charton

Chemistry · Physical Sciences

20h-index1.7kcitations61works2.02yr avg
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Research Topics

Analytical Chemistry and Chromatography(10), Synthesis and Characterization of Heterocyclic Compounds(9), Synthesis and biological activity(7), Chemical Synthesis and Analysis(7), Computational Drug Discovery Methods(6)

Publications61 total

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2
European Journal of Medicinal Chemistry·2025
Anti Sars-Cov-2 Antiviral Activity Provided by a New Chemotype that Opens the S2* Pocket of the 3cl Protease
SSRN Electronic Journal·2025Open Access
N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease
European Journal of Medicinal Chemistry·2024· 5 citedOpen Access
Identification of new correctors for traffic-defective ABCB4 variants by a high-content screening approach
Communications Biology·2024· 4 citedOpen Access
Capillary electrokinetic chromatography for chiral separation of potential SARS‐CoV‐2 3CL protease inhibitors
Electrophoresis·2024· 1 citedOpen Access
CCDC 2218737: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Discovery, Structure–Activity Relationships, and In Vivo Activity of Dihydropyridone Agonists of the Bile Acid Receptor TGR5
Journal of Medicinal Chemistry·2023· 7 cited
Identification of correctors for traffic-defective ABCB4 variants by a high-throughput screening approach
Journal of Hepatology·2023
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses
European Journal of Medicinal Chemistry·2023· 16 citedOpen Access
Farnesoid X Receptor Activation in Brain Alters Brown Adipose Tissue Function via the Sympathetic System
Frontiers in Molecular Neuroscience·2022· 18 citedOpen Access
Identification of indole-based activators of insulin degrading enzyme
European Journal of Medicinal Chemistry·2021· 9 citedOpen Access
Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry
Molecules·2021· 4 citedOpen Access
NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment
Angewandte Chemie·2021· 3 cited
NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment
Angewandte Chemie International Edition·2021· 43 citedOpen Access
Supercritical fluid chromatography and liquid chromatography for isomeric separation of a multiple chiral centers analyte
Journal of Chromatography A·2021· 17 cited
Farnesoid X Receptor activation in brain alters brown adipose tissue function via the sympathetic system
2021· 4 citedOpen Access
Hypothalamic bile acid-TGR5 signaling protects from obesity
Cell Metabolism·2021· 186 citedOpen Access
Electrophoretic separation of multiple chiral center analyte with a three cyclodextrins mixture
Electrophoresis·2021· 4 cited
Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure–Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor
Journal of Medicinal Chemistry·2021· 14 cited
Modulators of hERAP2 discovered by high-throughput screening
European Journal of Medicinal Chemistry·2020· 17 citedOpen Access
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Frequent Co-authors

Benoît Déprez(33), Florence Leroux(18), Rebecca Deprez‐Poulain(17), Bart Staels(12), Valérie Landry(10), Nathalie Hennuyer(9), Emmanuelle Lipka(9), Anne Tailleux(8), Catherine Piveteau(8), Adrien Herlédan(8), Sophie Girault‐Mizzi(7), Christian Sergheraert(7), Damien Bosc(6), Julie Dumont(6), Isabelle Duplan(5), François‐Xavier Cantrelle(5), Vanessa Hoguet(5), Sophie Lestavel(5), Rajâa Boulahjar(5), Terence Beghyn(5)