Brett Connolly

United States Military Academy — United States

Medicine · Health Sciences

21h-index3.6kcitations53works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(13), Neuroscience and Neuropharmacology Research(7), Computational Drug Discovery Methods(7), Medical Imaging Techniques and Applications(7), Viral Infections and Outbreaks Research(4)

Publications53 total

In Vivo Evaluation and Dosimetry Estimate for a High Affinity Affibody PET Tracer Targeting PD-L1
Molecular Imaging and Biology·2020· 36 cited
Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease
Neurobiology of Aging·2017· 53 cited
[P4–055]: IN VITRO BINDING STUDIES TO EVALUATE THE NFT‐SPECIFICITY OF [<sup>3</sup>H]MK‐6240 AND [<sup>3</sup>H]AV‐1451 BINDING IN SUBCORTICAL REGIONS OF HUMAN AD BRAIN
Alzheimer s & Dementia·2017
Vascular Imaging of Matrix Metalloproteinase Activity as an Informative Preclinical Biomarker of Drug-induced Vascular Injury
Toxicologic Pathology·2017· 9 citedOpen Access
[IC‐P‐207]: IN VITRO BINDING STUDIES TO EVALUATE THE NFT‐SPECIFICITY OF [<sup>3</sup>H]MK‐6240 AND [<sup>3</sup>H]AV‐1451 BINDING IN SUBCORTICAL REGIONS OF THE HUMAN AD BRAIN
Alzheimer s & Dementia·2017· 2 citedOpen Access
In Vivo Imaging of the Programmed Death Ligand 1 by <sup>18</sup>F PET
Journal of Nuclear Medicine·2017· 100 cited
Synthesis and preliminary PET imaging studies of [18F]MK-6240: A radiotracer for imaging neurofibrillary tangles (NFTs) in Alzheimer's disease
2016
IC‐P‐199: Comparing [<sup>3</sup>H]MK‐6240 and [<sup>3</sup>H]AV‐1451(T‐807) In <i>In vitro</i> Binding Studies in Brain Tissues
Alzheimer s & Dementia·2016
IC‐P‐187: Discovery and First‐in‐Human Evaluation of the TAU‐imaging PET Radiotracer [<sup>18</sup>F]MK‐6240
Alzheimer s & Dementia·2016· 1 cited
P1‐246: Discovery and First‐in‐Human Evaluation of the TAU‐Imaging PET Radiotracer [<sup>18</sup>F]MK‐6240
Alzheimer s & Dementia·2016
P1‐244: Comparing [<sup>3</sup>H]MK‐6240 and [<sup>3</sup>H]AV‐1451(T‐807) in <i>in VITRO</i> Binding Studies in Brain Tissues
Alzheimer s & Dementia·2016Open Access
Preclinical Characterization of<sup>18</sup>F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles
Journal of Nuclear Medicine·2016· 278 citedOpen Access
Investigation into Use of Positron Emission Tomography (PET) as an In Vivo Imaging Tool to Quantify PD-L1 Tumor Expression Levels
2016· 1 cited
Discovery of 6-(Fluoro-<sup>18</sup><i>F</i>)-3-(1<i>H</i>-pyrrolo[2,3-<i>c</i>]pyridin-1-yl)isoquinolin-5-amine ([<sup>18</sup>F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)
Journal of Medicinal Chemistry·2016· 175 cited
Targeting of deep-brain structures in nonhuman primates using MR and CT Images
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2015· 4 cited
Optical Imaging Biomarkers of Drug-Induced Vascular Injury
Molecular Imaging·2015· 9 citedOpen Access
Quantitative <i>In Vivo</i> Detection of <i>Chlamydia muridarum</i> Associated Inflammation in a Mouse Model Using Optical Imaging
Mediators of Inflammation·2015· 6 citedOpen Access
Non-Invasive Bioluminescence Imaging of β-Cell Function in Obese-Hyperglycemic [ob/ob] Mice
PLoS ONE·2014· 13 citedOpen Access
Pyroglutamate-Modified Amyloid-β Protein Demonstrates Similar Properties in an Alzheimer's Disease Familial Mutant Knock-In Mouse and Alzheimer's Disease Brain
Neurodegenerative Diseases·2013· 31 cited
Comparative Analysis of Folate Derived PET Imaging Agents with [<sup>18</sup>F]-2-Fluoro-2-deoxy-<scp>d</scp>-glucose Using a Rodent Inflammatory Paw Model
Molecular Pharmaceutics·2013· 27 cited
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Frequent Co-authors

Cyrille Sur(18), Zhizhen Zeng(17), Stacey O’Malley(16), Eric D. Hostetler(14), Patricia Miller(12), Idriss Bennacef(9), Jeffrey L. Evelhoch(9), Richard Hargreaves(8), David Hesk(8), Talakad G. Lohith(7), Shu-An Lin(7), Bohumil Bednář(7), Tsing‐Bau Chen(7), Amy Vanko(6), Abbas Walji(6), Liza Gantert(6), Mona Purcell(6), Aileen Soriano(6), Terence G. Hamill(5), Cristian Salinas(5)