Johan Saldeen

Uppsala University — Sweden

Medicine · Health Sciences

15h-index971citations25works2.02yr avg
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Research Topics

Pancreatic function and diabetes(11), Diabetes and associated disorders(8), Cell death mechanisms and regulation(4), Pluripotent Stem Cells Research(4), PARP inhibition in cancer therapy(3)

Publications25 total

Decreasing Tacrolimus Concentrations in Routine Therapeutic Drug Monitoring Data Indicate Adherence to Updated Therapeutic Goals
Biomedicines·2026Open Access
Response to: Shift happens: The utility of external quality assessment data in evaluating folate lot changes. doi.org/10.1515/cclm-2025-1569
Clinical Chemistry and Laboratory Medicine (CCLM)·2025Open Access
Recent decline in patient serum folate test levels using Roche Diagnostics Folate III assay
Clinical Chemistry and Laboratory Medicine (CCLM)·2025· 4 citedOpen Access
Pediatric reference intervals for serum folate and cobalamin based on a European population without exposure to folic acid fortification
Scandinavian Journal of Clinical and Laboratory Investigation·2024· 4 citedOpen Access
Seasonal Variation of Ferritin among Swedish Blood Donors
Laboratory Medicine·2022· 1 cited
Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb
Differentiation·2008· 12 cited
The SHB Adapter Protein Is Required for Normal Maturation of Mesoderm during in Vitro Differentiation of Embryonic Stem Cells
Journal of Biological Chemistry·2006· 20 citedOpen Access
The Role of the Adapter Protein SHB in Embryonic Stem Cell Differentiation Into the Pancreatic β-Cell and Endothelial Lineages
Humana Press eBooks·2006· 1 cited
IL-1β-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line
Diabetologia·2006· 15 citedOpen Access
SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells
Biochemical and Biophysical Research Communications·2006· 8 cited
p38 MAPK inhibits JNK2 and mediates cytokine-activated iNOS induction and apoptosis independently of NF-KB translocation in insulin-producing cells.
PubMed·2004· 27 cited
Nicotinamide- and caspase-mediated inhibition of poly(ADP-ribose) polymerase are associated with p53-independent cell cycle (G2) arrest and apoptosis
Molecular and Cellular Biochemistry·2003· 36 cited
Cytokine-induced apoptosis and necrosis are preceded by disruption of the mitochondrial membrane potential (Δψm) in pancreatic RINm5F cells: prevention by Bcl-2
Molecular and Cellular Endocrinology·2002· 118 cited
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis
Biochemical Pharmacology·2001· 99 cited
Cytokines Induce Both Necrosis and Apoptosis via a Common Bcl-2-Inhibitable Pathway in Rat Insulin-Producing Cells*
Endocrinology·2000· 160 cited
LIPOSOME-MEDIATED TRANSFER OF IL-1 RECEPTOR ANTAGONIST GENE TO DISPERSED ISLET CELLS DOES NOT PREVENT RECURRENCE OF DISEASE IN SYNGENEICALLY TRANSPLANTED NOD MICE
Cytokine·2000· 9 cited
The Acid Sphingomyelinase Inhibitor SR33557 Counteracts TNF-α-Mediated Potentiation of IL-1β-Induced NF-κB Activation in the Insulin-Producing Cell Line RINm5F
Autoimmunity·2000· 17 cited
Novel Experimental Strategies to Prevent the Development of Type 1 Diabetes Mellitus
Upsala Journal of Medical Sciences·2000· 28 citedOpen Access
Islet expression of perforin, Fas/Apo-1 and interleukin-1 converting enzyme (ICE) in non-obese diabetic (NOD) mice
Immunology Letters·1998· 21 cited
Nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(ADP-ribose) polymerase
Molecular and Cellular Endocrinology·1998· 46 cited
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Frequent Co-authors

Nils Welsh(13), Anders Larsson(4), Décio L. Eizirik(3), Eva Strandell(3), Vı́tězslav Křı́ž(3), Nina Ågren(3), Michael Welsh(3), Malin Flodström‐Tullberg(2), Arne Andersson(2), Claes Hellerström(2), Andreea Barbu(2), Karsten Buschard(2), Linda Tillmar(2), Ella Karlsson(2), Stellan Sandler(2), Björn Åkerblom(2), Frida Duell(2), Boris A. Margulis(1), Lisa Borg(1), Helena Jernberg‐Wiklund(1)