Nils Welsh

Medicine · Health Sciences

47h-index8.7kcitations198works5.52yr avg
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Research Topics

Pancreatic function and diabetes(134), Diabetes and associated disorders(64), Metabolism, Diabetes, and Cancer(32), Diet, Metabolism, and Disease(31), Diabetes Management and Research(22)

Publications198 total

From Discussion to Decision
2025
GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine
International Journal of Molecular Sciences·2024· 11 citedOpen Access
The selective NOX4 inhibitor GLX7013159 decreases blood glucose concentrations and human beta-cell apoptotic rates in diabetic NMRI nu/nu mice transplanted with human islets
Free Radical Research·2023· 5 citedOpen Access
CLEC11A improves insulin secretion and promotes cell proliferation in human beta-cells
Journal of Molecular Endocrinology·2023· 4 citedOpen Access
Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine
Frontiers in Endocrinology·2023· 4 citedOpen Access
Are off-target effects of imatinib the key to improving beta-cell function in diabetes?
Upsala Journal of Medical Sciences·2022· 3 citedOpen Access
Pharmacological Inhibition of NOX4 Improves Mitochondrial Function and Survival in Human Beta-Cells
Biomedicines·2021· 13 citedOpen Access
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
Clinical Science·2021· 9 citedOpen Access
ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation
Diabetologia·2021· 24 citedOpen Access
The importance of the ZBED6‐IGF2 axis for metabolic regulation in mouse myoblast cells
The FASEB Journal·2020· 46 citedOpen Access
Dissection of the cellular function of the ZBED6 transcription factor in mouse myoblast cells using gene editing, RNAseq and proteomics
2019· 1 citedOpen Access
The protein synthesis inhibitor brusatol normalizes high‐fat diet‐induced glucose intolerance in male C57BL/6 mice: role of translation factor eIF5A hypusination
The FASEB Journal·2018· 15 citedOpen Access
The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro
PLoS ONE·2018· 71 citedOpen Access
ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells
The FASEB Journal·2018· 17 cited
BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells
Proceedings of the National Academy of Sciences·2018· 57 citedOpen Access
Addition of exogenous sodium palmitate increases the IAPP/insulin mRNA ratio via GPR40 in human EndoC-βH1 cells
Upsala Journal of Medical Sciences·2017· 13 citedOpen Access
EndoC-βH1 cells display increased sensitivity to sodium palmitate when cultured in DMEM/F12 medium
Islets·2017· 33 citedOpen Access
Changes in myotube development and mitochondrial activity in mouse C2C12 cells after ZBED6 silencing is largely due to increased IGF2 expression
2017
PTB and TIAR binding to insulin mRNA 3′- and 5′UTRs; implications for insulin biosynthesis and messenger stability
Heliyon·2016· 14 citedOpen Access
Aromatic malononitriles stimulate the resistance of insulin-producing beta-cells to oxidants and inflammatory cytokines
European Journal of Pharmacology·2016· 11 cited
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Frequent Co-authors

Décio L. Eizirik(22), Stellan Sandler(9), Claes Hellerström(8), Johan Saldeen(6), Michael Welsh(6), Eva Strandell(6), Klaus Bendtzen(4), Per‐Olof Berggren(4), Per‐Ola Carlsson(4), S. Sandler(3), Daniël Pipeleers(3), Malin Flodström‐Tullberg(3), Arne Andersson(3), Lisa Borg(3), Robert Hägerkvist(3), Åke Sjöholm(3), Miriam Cnop(2), Carina Carlsson(2), Linda Tillmar(2), Dariush Mokhtari(2)