Magnus Chan

University of British Columbia — Canada

Medicine · Health Sciences

2h-index16citations22works0.52yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(14), Ion channel regulation and function(10), Blood Pressure and Hypertension Studies(4), Heart Rate Variability and Autonomic Control(4), Neuroscience and Neural Engineering(4)

Publications22 total

A physiologically-relevant intermediate state structure of a voltage-gated potassium channel
Nature Communications·2025· 1 citedOpen Access
Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077
Molecular Pharmacology·2025Open Access
Graded activation of mutant K41C-KCNE1:KCNQ1 channel complexes by mefenamic acid
Channels·2025Open Access
Effect of amphetamines on blood pressure
Cochrane Database of Systematic Reviews·2025· 1 citedOpen Access
Effect of adrenergic agonist oral decongestants on blood pressure
Cochrane Database of Systematic Reviews·2025· 1 citedOpen Access
BPS2025 - Electrophysiological and structural characterization of the binding of the cardiac ion channel blocker UCL2077 to KCNQ1 channels
Biophysical Journal·2025
BPS2025 - Dual effects of mefenamic acid on the IKs molecular complex
Biophysical Journal·2025
BPS2025 - Structural investigation of an intermediate state of KCNQ1
Biophysical Journal·2025
BPS2025 - Electrophysiological and structural characterization of the binding of the cardiac ion channel blocker UCL2077 to KCNQ1 channels
Biophysical Journal·2025
Dual effects of mefenamic acid on the <i>I</i><sub>Ks</sub> molecular complex
British Journal of Pharmacology·2024· 2 citedOpen Access
Author Response: A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
eLife·2023Open Access
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
Author Response: A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
Author Response: A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
eLife·2023· 8 citedOpen Access
A generic binding pocket for small molecule <i> I <sub>Ks</sub> </i> activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
2023Open Access
A mutational and modeling study of a binding pocket for IKs activators between KCNQ1 and KCNE1
Biophysical Journal·2023
Effect of adrenergic agonist oral decongestants on blood pressure
Cochrane Database of Systematic Reviews·2021· 2 cited
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Frequent Co-authors

Jodene Eldstrom(17), David Fedida(17), Daniel Sastre(12), Marc Pourrier(12), Harutyun Sahakyan(10), Yundi Wang(10), Ying Dou(9), Vitya Vardanyan(9), Jocelyn Chan(4), Filip Van Petegem(4), Ying Dou(4), James M Wright(3), Efthymios Kyriakis(3), Julia Schauer(3), E. Kyriakis(2), Sophia Russo(2), Fariba Ataei(2), Steven Molinarolo(2), Vitya A. Vardanyan(2), Gavin WK Wong(1)