Philip J. Papst

MBio Diagnostics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index2.6kcitations23works0.02yr avg
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Research Topics

Signaling Pathways in Disease(6), Histone Deacetylase Inhibitors Research(4), Cardiac Ischemia and Reperfusion(3), Biochemical and Molecular Research(3), Cardiac electrophysiology and arrhythmias(2)

Publications23 total

An Innovative Portable Biosensor System for the Rapid Detection of Freshwater Cyanobacterial Algal Bloom Toxins
Environmental Science & Technology·2018· 61 citedOpen Access
A high-performance liquid chromatography assay for quantification of cardiac myosin heavy chain isoform protein expression
Analytical Biochemistry·2010· 10 cited
Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2009· 30 cited
Canonical Transient Receptor Potential Channels Promote Cardiomyocyte Hypertrophy through Activation of Calcineurin Signaling
Journal of Biological Chemistry·2006· 277 citedOpen Access
Regulation of Cardiac Stress Signaling by Protein Kinase D1
Molecular and Cellular Biology·2006· 153 citedOpen Access
Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5
Molecular and Cellular Biology·2004· 515 citedOpen Access
Small molecule phenotypic screen using a MEF2/ HDAC5 mammalian two-hybrid assay
Journal of Cardiac Failure·2004
Cardioprotective Effect Afforded by Transient Exposure to Phosphodiesterase III Inhibitors
Circulation·2001· 107 cited
Hepatic maturation in differentiating embryonic stem cells in vitro
FEBS Letters·2001· 432 cited
Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
Proceedings of the National Academy of Sciences·2001· 70 citedOpen Access
Role of Phasic Dynamism of p38 Mitogen-Activated Protein Kinase Activation in Ischemic Preconditioning of the Canine Heart
Circulation Research·2001· 102 cited
Inhibition of Nitric Oxide Synthesis Induces Coronary Vascular Remodeling and Cardiac Hypertrophy Associated with the Activation of p70 S6 Kinase in Rats
Cardiovascular Drugs and Therapy·2000· 20 cited
Chronic Treatment with FK506 Increases p70 S6 Kinase Activity Associated with Reduced Nitric Oxide Synthase Activity in Rabbit Hearts
Cardiovascular Drugs and Therapy·2000· 6 cited
MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes
Proceedings of the National Academy of Sciences·1999· 136 citedOpen Access
l-Asparaginase Inhibits the Rapamycin-Targeted Signaling Pathway
Biochemical and Biophysical Research Communications·1999· 48 cited
Amino Acid-dependent Control of p70s6k
Journal of Biological Chemistry·1999· 203 citedOpen Access
Cdc2-Cyclin B Phosphorylates p70 S6 Kinase on Ser411at Mitosis
Journal of Biological Chemistry·1998· 60 citedOpen Access
Targeted disruption of p70<sup>s6k</sup>defines its role in protein synthesis and rapamycin sensitivity
Proceedings of the National Academy of Sciences·1998· 177 citedOpen Access
Overexpression of wild type p70 S6 kinase interferes with cytokinesis
Oncogene·1997· 9 cited
p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229
The Journal of Immunology·1996· 27 citedOpen Access
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Frequent Co-authors

Naohiro Terada(13), Timothy A. McKinsey(5), Erwin W. Gelfand(4), Hiroshi Asanuma(4), Tsunehiko Kuzuya(4), Eric N. Olson(3), Yasuhiko Iiboshi(3), Gary L. Johnson(3), Tetsuo Minamino(3), Masafumi Kitakaze(3), Akiko Ogai(3), Rick B. Vega(2), Brooke C. Harrison(2), Leonard I. Zon(2), David B. Hood(2), Joseph Chapo(2), Hideki Kawasome(2), Saiphone Webb(2), Craig F. Plato(2), Shoji Sanada(2)