Timothy A. McKinsey

University of Colorado Boulder — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

76h-index22.0kcitations328works5.02yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(108), Signaling Pathways in Disease(83), Peptidase Inhibition and Analysis(66), Cardiac Fibrosis and Remodeling(39), Protein Degradation and Inhibitors(37)

Publications328 total

Waging war against cardiac fibrosis by targeting the anthrax toxin receptor
Nature Cardiovascular Research·2025
Low Dose GLP-1 Therapy Attenuates Pathological Cardiac and Hepatic Remodelling in HFpEF Independent of Weight Loss
2025· 1 citedOpen Access
HDAC11 inhibition effects on β2AR localization, signaling and function in airway smooth muscle
2025
β <sub>1</sub> - and β <sub>2</sub> -adrenergic Receptor Haplotypes Regulate Therapeutic Responses to Placebo and the Biased Ligand β-blocker Bucindolol
2025Open Access
Abstract Wed132: High-content imaging and machine learning predicts profibrotic phenotype in human cardiac fibroblasts
Circulation Research·2025
Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture
Cell Reports Methods·2025· 2 citedOpen Access
How to Facilitate Seamless Translation from Basic Concepts to New Heart Failure Drugs. A Scientific Statement of the Heart Failure Association of the ESC
European Journal of Heart Failure·2025· 5 citedOpen Access
Transcriptional signature of cardiac myocyte recovery in mice and human reveals persistent upregulation of epigenetic factors
Epigenetics·2025· 1 citedOpen Access
Regulation of Cardiac Fibroblast Signaling by HDAC11-Reversible Myristoylation of an AKAP
Journal of Molecular and Cellular Cardiology Plus·2025Open Access
Modulating the Secretome of Fat to Treat Heart Failure
Circulation Research·2025· 2 cited
Salt-inducible Kinase Regulation of Adipose Tissue Metabolism
Endocrinology·2025Open Access
Biocompatibility Assessment of an Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel for Cardiac Tissue Engineering Applications
ACS Applied Bio Materials·2025· 4 cited
Myocardial transcriptomic and proteomic landscapes across the menopausal continuum in a murine model of chemically induced accelerated ovarian failure
Physiological Genomics·2025Open Access
Cell Painting and Machine Learning Distinguish Fibroblasts From Nonfailing and Failing Human Hearts
Circulation·2025· 4 cited
Heart Rate Reduction Is Associated With Reverse Left Ventricular Remodeling and Mechanism-Specific Molecular Phenotypes in Dilated Cardiomyopathy
Circulation Heart Failure·2025· 1 citedOpen Access
Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Deuterium labeling enables proteome wide turnover kinetics analysis in cell culture
2025· 1 citedOpen Access
BRD4 inhibition rewires cardiac macrophages toward a protective phenotype marked by low MHC class II expression
American Journal of Physiology-Heart and Circulatory Physiology·2024· 7 citedOpen Access
Logic-based machine learning predicts how escitalopram attenuates cardiomyocyte hypertrophy
2024Open Access
Abstract 4141686: Chromatin Remodeling Drives Immune-Fibroblast Cell Communication in Heart Failure
Circulation·2024
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Frequent Co-authors

Eric N. Olson(30), Chun Li Zhang(9), Maria A. Cavasin(7), Jianrong Lu(5), James A. Richardson(5), Kurt R. Stenmark(5), Christopher L. Antos(4), Rhonda Bassel‐Duby(4), Norbert Frey(4), Rick B. Vega(4), Michael E. Yeager(4), Chun‐Li Zhang(3), Joseph A. Hill(3), Dean W. Ballard(3), Rebekka L. Nicol(3), Philip J. Papst(3), Deepak Srivastava(3), Saptarsi M. Haldar(3), Mark Y. Jeong(3), Todd R. Horn(3)