A. Tolstikova

Universität Hamburg — Germany

Materials Science · Physical Sciences

18h-index2.3kcitations76works5.52yr avg
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Research Topics

Enzyme Structure and Function(28), Computational Drug Discovery Methods(25), SARS-CoV-2 and COVID-19 Research(17), Advanced X-ray Imaging Techniques(11), Protein Structure and Dynamics(8)

Publications75 total

Observation of early events in the photoactivation of Myxobacterial phytochrome using time-resolved serial femtosecond crystallography
Communications Chemistry·2025· 3 citedOpen Access
Real-time data processing for serial crystallography experiments
IUCrJ·2024· 5 citedOpen Access
SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds
Nature Communications·2024· 8 citedOpen Access
Data reduction in protein serial crystallography
IUCrJ·2024· 6 citedOpen Access
Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam
Nature Communications·2023· 24 citedOpen Access
Room-temperature structural studies of SARS-CoV-2 protein, NendoU, with an X-ray free-electron laser
Acta Crystallographica Section A Foundations and Advances·2023· 1 cited
Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser
Structure·2023· 16 citedOpen Access
Heterogeneity in the M. tuberculosis β-Lactamase Inhibition by Sulbactam
Research Square (Research Square)·2023· 1 citedOpen Access
Heterogeneity in the <i>M. tuberculosis</i> β-lactamase inhibition by Sulbactam
2022Open Access
Electrically stimulated droplet injector for reduced sample consumption in serial crystallography
Biophysical Reports·2022· 10 citedOpen Access
Cooperative allostery and structural dynamics of streptavidin at cryogenic- and ambient-temperature
Communications Biology·2022· 21 citedOpen Access
Cooperative Allostery and Structural Dynamics of Streptavidin at Cryogenic- and Ambient-temperature
2021· 4 citedOpen Access
Pink-beam serial femtosecond crystallography for accurate structure-factor determination at an X-ray free-electron laser
IUCrJ·2021· 27 citedOpen Access
Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography
IUCrJ·2021· 82 citedOpen Access
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing
Structure·2021· 44 citedOpen Access
Pink-beam serial femtosecond crystallography for accurate structure factor determination at an X-ray free-electron laser
Acta Crystallographica Section A Foundations and Advances·2021· 2 citedOpen Access
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 4-(2-hydroxyethyl)phenol
2021
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with p-hydroxybenzaldehyde
2021
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 3, 4-Dihydroxybenzoic acid, methyl ester
2021
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
Science·2021· 354 citedOpen Access
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Frequent Co-authors

Oleksandr Yefanov(34), Henry N. Chapman(31), Valerio Mariani(23), J. Knoška(20), Anton Barty(20), D. Oberthüer(19), Salah Awel(17), Y. Gevorkov(16), Mark S. Hunter(16), Alke Meents(15), J. Lieske(14), F. Koua(14), W. Brehm(14), Thomas A. White(14), Luca Gelisio(13), P. Reinke(12), M. Galchenkova(12), Thomas J. Lane(11), Sven Falke(11), H. Brognaro(11)