John Ferbas

Amgen (United States) — United States

Immunology and Microbiology · Life Sciences

24h-index2.4kcitations68works3.12yr avg
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Research Topics

HIV Research and Treatment(19), Monoclonal and Polyclonal Antibodies Research(16), Immune Cell Function and Interaction(16), T-cell and B-cell Immunology(9), Single-cell and spatial transcriptomics(9)

Publications68 total

Elucidating Catalytic Bioluminescence of Mammalian Gaussia Luciferase through Mutant and Ancestral Analysis
ACS Chemical Biology·2026
PNPLA3-I148M is a neomorph that interferes with two primary hepatic triglyceride clearance pathways
Cell Reports·2025Open Access
Novel mechanistic insights for catalytic bioluminescence of mammalian Gaussia Luciferase through mutant and ancestral analysis
2025· 1 cited
Abstract 2651 PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
Journal of Biological Chemistry·2025Open Access
PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
2024· 1 citedOpen Access
RAB18 regulates extrahepatic siRNA-mediated gene silencing efficacy
Molecular Therapy — Nucleic Acids·2024Open Access
The fatty liver disease–causing protein PNPLA3-I148M alters lipid droplet–Golgi dynamics
Proceedings of the National Academy of Sciences·2024· 23 citedOpen Access
RAB18 Regulates Extrahepatic SiRNA-Mediated Gene Silencing Efficacy
2024Open Access
The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics
2023· 8 citedOpen Access
Use of In Vitro Human Skin Models to Assess Potential Immune Activation In Response to Biotherapeutic Attributes and Process-related Impurities
Journal of Pharmaceutical Sciences·2022· 8 cited
Non-clinical similarity of biosimilar ABP 798 with rituximab reference product
Biologicals·2021· 3 citedOpen Access
Functional and Nonclinical Similarity of ABP 980, a Biosimilar of Trastuzumab
Pharmaceutical Research·2019· 17 citedOpen Access
Impact of Precipitation of Antibody Therapeutics After Subcutaneous Injection on Pharmacokinetics and Immunogenicity
Journal of Pharmaceutical Sciences·2019· 26 cited
Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus
Lupus Science & Medicine·2016· 71 citedOpen Access
Role of receptor occupancy assays by flow cytometry in drug development
Cytometry Part B Clinical Cytometry·2015· 33 citedOpen Access
Recommendations for the development and validation of flow cytometry‐based receptor occupancy assays
Cytometry Part B Clinical Cytometry·2015· 24 citedOpen Access
Treatment of systemic lupus erythematosus patients with the BAFF antagonist “peptibody” blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and phase 1b trials
Arthritis Research & Therapy·2015· 57 citedOpen Access
Endotoxin Neutralization as a Biomonitor for Inflammatory Bowel Disease
PLoS ONE·2013· 10 citedOpen Access
A novel assay to measure <scp>B</scp> cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus
British Journal of Clinical Pharmacology·2013· 17 citedOpen Access
Three‐Dimensional Second‐Harmonic Generation Imaging of Fibrillar Collagen in Biological Tissues
Current Protocols in Cytometry·2012· 3 cited
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Frequent Co-authors

Janis V. Giorgi(11), Lance E. Hultin(7), Joseph B. Margolick(6), Steven J. Swanson(6), John Thomas(5), Roger Detels(5), Jiansong Xie(5), Ingrid Schmid(4), Alison Logar(4), Shelley Sims Belouski(4), Daniel T. Mytych(4), Kathie Grovit‐Ferbas(4), Kenneth D. Bauer(3), Lawrence P. Park(3), Mary Ann Hausner(3), Jose L. Matud(3), Charles R. Rinaldo(3), Álvaro Muñoz(3), Arunan Kaliyaperumal(3), James Chung(3)