Martin Bertschinger

Ichnos Sciences (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index661citations27works1.52yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(16), RNA Interference and Gene Delivery(11), Monoclonal and Polyclonal Antibodies Research(9), Virus-based gene therapy research(8), Advanced biosensing and bioanalysis techniques(5)

Publications27 total

Development of a 10 g/L process for a difficult-to-express multispecific antibody format using a holistic process development approach
Journal of Biotechnology·2024· 3 citedOpen Access
Alternative splicing for tuneable expression of protein subunits at desired ratios
mAbs·2024· 2 citedOpen Access
Viral inactivation for pH-sensitive antibody formats such as multi-specific antibodies
Journal of Biotechnology·2024· 1 cited
Expression of Bispecific Antibodies Using Cellular Display
Methods in molecular biology·2024
Benchtop Bioreactors in Mammalian Cell Culture: Overview and Guidelines
Methods in molecular biology·2021· 7 cited
Generation of homogeneous cell populations with tunable levels of transgene expression
Journal of Biotechnology·2020· 2 cited
SPLICELECT™: an adaptable cell surface display technology based on alternative splicing allowing the qualitative and quantitative prediction of secreted product at a single-cell level
mAbs·2020· 11 citedOpen Access
Corrigendum to “Analytical assessment of clonal derivation of eukaryotic/CHO cell populations” [J. Biotechnol. 286 (2018) 17–26]
Journal of Biotechnology·2019
Analytical assessment of clonal derivation of eukaryotic/CHO cell populations
Journal of Biotechnology·2018· 8 cited
A novel bispecific antibody for HER2+ breast cancer: The BEAT GBR 1302
2016· 1 cited
Antibody disulfide bond reduction during process development: Insights using a scale-down model process
BMC Proceedings·2015· 6 citedOpen Access
Use of a new genetic element to improve expression level of cell lines for recombinant protein production
BMC Proceedings·2015· 3 citedOpen Access
A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies
Journal of Hematology & Oncology·2014· 32 citedOpen Access
BEAT® the bispecific challenge: a novel and efficient platform for the expression of bispecific IgGs
BMC Proceedings·2013· 27 citedOpen Access
The Kinetics of Polyethylenimine-Mediated Transfection in Suspension Cultures of Chinese Hamster Ovary Cells
Molecular Biotechnology·2008· 25 cited
The Role of the Sumoylation Pathway in Transient and Stable Recombinant Protein Expression in Chinese Hamster Ovary Cells
2007
1000 Non-instrumented Bioreactors in a Week
2007· 8 cited
Stability and Cytogenetic Characterization of Recombinant CHO Cell Lines Established by Microinjection and Calcium Phosphate Transfection
2007· 1 cited
Release of Plasmid-DNC from PEI/DNA Particles
2007
Multiple glycerol shocks increase the calcium phosphate transfection of non-synchronized CHO cells
Biotechnology Letters·2006· 19 citedOpen Access
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Frequent Co-authors

Florian Μ. Wurm(12), Pierre Moretti(9), David L. Hacker(8), Roberto Giovannini(6), Martin Jordan(5), Christel Aebischer-Gumy(5), Madiha Derouazi(3), Gaurav Backliwal(3), Arnaud Schertenleib(3), Julie Macoin(3), Romain Ollier(3), Natalie Müller(2), Danielle Martinet(2), R. Flaction(2), M. Wicht(2), J. Beckmann(2), Samuel Y. Hou(2), Jonathan Back(2), Paul Wassmann(2), Stanislas Blein(2)