Gaurav Backliwal

Indian Institute of Technology Delhi — India

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index699citations15works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(8), Virus-based gene therapy research(5), RNA Interference and Gene Delivery(5), CAR-T cell therapy research(4), Advanced biosensing and bioanalysis techniques(3)

Publications15 total

Comparison of lovastatin synthesis using glucose and lactose by metabolic flux analysis
2012
High Cell Density Transient Gene Expression in HEK 293 EBNA Cells
2011· 1 cited
Recombinant Antibody Yield Over 2 g/L by Transient Transfection of HEK 293 EBNA Cells in a Fed-Batch Process
2011· 3 cited
A Transient Gene Expression Process with Recombinant Antibody Titer of 0.5 g/L in CHO Cells
2011
Optimization and Comparison of Different DNA Methyl Transferase and Histone Deacetylase Inhibitors for Enhancing Transient Protein Expression
2010
Towards the Use of CHO Produced Recombinant Extracellular Matrix Proteins as Bioactive Elements in a 3-D Scaffold for Tissue Engineering
2010
A Serum-Free, Transient Transfection System for Enhancing Production of Recombinant Antibodies in Mammalian Cells
2010
Coexpression of acidic fibroblast growth factor enhances specific productivity and antibody titers in transiently transfected HEK293 cells
New Biotechnology·2008· 27 citedOpen Access
Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions
Nucleic Acids Research·2008· 229 citedOpen Access
Valproic acid: A viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures
Biotechnology and Bioengineering·2008· 168 cited
Development of high-titer transient gene expression processes for manufacturing recombinant proteins
Infoscience (Ecole Polytechnique Fédérale de Lausanne)·2008· 2 citedOpen Access
High‐density transfection with HEK‐293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEI
Biotechnology and Bioengineering·2007· 152 citedOpen Access
Release of Plasmid-DNC from PEI/DNA Particles
2007
Disassembly of polyethylenimine-DNA particles in vitro: Implications for polyethylenimine-mediated DNA delivery
Journal of Controlled Release·2006· 113 citedOpen Access
Polyethylenimine-based quality control assay for plasmid DNA
Analytical Biochemistry·2006· 4 citedOpen Access

Frequent Co-authors

Florian Μ. Wurm(13), Markus Hildinger(7), David L. Hacker(6), Sarah Wulhfard(3), María de Jesús(3), Martin Bertschinger(3), Martin Jordan(3), Lucia Baldi(3), Sébastien Chenuet(2), Fanny Delegrange(2), Arnaud Schertenleib(2), Divor Kiseljak(2), Yashas Rajendra(2), Ivan Kuettel(1), Vivek Hasija(1), Maria DeJesus(1), Cédric Burki(1), Ivan Küttel(1), Sanjay Kumar(1), James Gomes(1)