Markus Hildinger

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.7kcitations42works0.02yr avg
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Research Topics

Virus-based gene therapy research(24), RNA Interference and Gene Delivery(13), Viral Infectious Diseases and Gene Expression in Insects(11), CRISPR and Genetic Engineering(8), CAR-T cell therapy research(7)

Publications42 total

Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia
Journal for ImmunoTherapy of Cancer·2021· 23 citedOpen Access
Cutting Edge: Differential Fine-Tuning of IL-2– and IL-15–Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor
The Journal of Immunology·2017· 27 cited
Abdeckung von Verschnittresten unter Konnektivitätsbedingungen
OPUS Publication Server of the University of Stuttgart (University of Stuttgart)·2015Open Access
Algorithmen zur Optimierung von Packungsproblemen
OPUS Publication Server of the University of Stuttgart (University of Stuttgart)·2014Open Access
A Transient Gene Expression Process with Recombinant Antibody Titer of 0.5 g/L in CHO Cells
2011
Optimization and Comparison of Different DNA Methyl Transferase and Histone Deacetylase Inhibitors for Enhancing Transient Protein Expression
2010
A Serum-Free, Transient Transfection System for Enhancing Production of Recombinant Antibodies in Mammalian Cells
2010
Isolation and evaluation of novel adeno-associated virus sequences from porcine tissues
Gene Therapy·2009· 52 cited
Coexpression of acidic fibroblast growth factor enhances specific productivity and antibody titers in transiently transfected HEK293 cells
New Biotechnology·2008· 27 citedOpen Access
Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions
Nucleic Acids Research·2008· 229 citedOpen Access
Valproic acid: A viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures
Biotechnology and Bioengineering·2008· 168 cited
High‐density transfection with HEK‐293 cells allows doubling of transient titers and removes need for a priori DNA complex formation with PEI
Biotechnology and Bioengineering·2007· 152 citedOpen Access
High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells
Biotechnology Letters·2007· 63 citedOpen Access
RNA Interference–Mediated Suppression and Replacement of Human Rhodopsin In Vivo
The American Journal of Human Genetics·2007· 171 citedOpen Access
1020. AAV Delivery of Suppression and Replacement Constructs for Rhodopsin-Linked Autosomal Dominant Retinitis Pigmentosa
Molecular Therapy·2006Open Access
Advances in AAV-mediated gene transfer for the treatment of inherited disorders
European Journal of Human Genetics·2004· 39 cited
Impact of splice-site mutations of the human MDR1 cDNA on its stability and expression following retroviral gene transfer
Gene Therapy·2003· 10 cited
<i>In Vivo</i> Quantitative Noninvasive Imaging of Gene Transfer by Single-Photon Emission Computerized Tomography
Human Gene Therapy·2003· 34 cited
Efficient Trans-Splicing in the Retina Expands the Utility of Adeno-Associated Virus as a Vector for Gene Therapy
Human Gene Therapy·2003· 93 cited
Trans-Splicing AAV Vector System Expands the Packaging Capacity Of AAV Gene Therapy Vectors for Delivery of Large Transgenes to the Retina
2002
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Frequent Co-authors

Alberto Auricchio(13), Wolfram Ostertag(13), James M. Wilson(9), Florian Μ. Wurm(8), Gaurav Backliwal(7), Judith John(6), Erin E. O’Connor(5), Guangping Gao(5), Christel Baum(5), Lili Wang(4), Dorotheé von Laer(4), Sarah Wulhfard(3), María de Jesús(3), Roberto Calcedo(3), Boris Fehse(3), Christopher Baum(3), H-G Eckert(3), AJ Schilz(3), Birgit Vogt(3), Nicholas H. Hunt(3)