Edward J. Kelly

University of Washington — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

39h-index5.0kcitations154works1.72yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(28), 3D Printing in Biomedical Research(23), Drug Transport and Resistance Mechanisms(20), Renal and related cancers(10), Pluripotent Stem Cells Research(9)

Publications153 total

Potential integration of multiple organs-on-a-chip for comprehensive drug–drug interaction prediction
Expert Opinion on Drug Metabolism & Toxicology·2026
Differential retinoic acid responses across testicular development <i>in vitro</i>
2025Open Access
Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity
npj Microgravity·2025Open Access
Regulation of Renal Transporters by Pro-inflammatory Cytokines in Human Proximal Tubular Epithelial Cells: Identification of the Perpetrator and Mechanisms
2025Open Access
Effect of proinflammatory cytokines on intestinal drug transporters in human enteroid monolayers
Drug Metabolism and Disposition·2025· 1 cited
Pervasive food contaminant ochratoxin‐A induces energy crisis: Mitochondrial dysfunction in human primary proximal tubule cells
Toxicology Reports·2025Open Access
Human OAT1, OAT3, OAT4 and OATP1A2 Facilitate the Renal Accumulation of Ochratoxin A
Pharmaceutics·2025Open Access
Human OAT1, OAT3, OAT4 and OATP1A2 Facilitate the Renal Accumulation of Ochratoxin A
Preprints.org·2025Open Access
In vitro models of the male reproductive system: applications for developmental and reproductive toxicology
Toxicological Sciences·2025· 1 cited
Evaluation of toxicological mechanisms of ochratoxin-A in human primary proximal tubule epithelial cells
2025Open Access
Leveraging RNA-seq deconvolution to improve complex in vitro model characterization
Journal of Biological Chemistry·2025· 2 citedOpen Access
Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity
2025Open Access
Enhancing therapeutic strategies and drug development for patients with kidney disease
Expert Opinion on Drug Safety·2025· 1 citedOpen Access
Corrigendum to ‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Application of enteroid monolayers to evaluate potential pharmacokinetic oregano oil-drug interactions
Drug Metabolism and Pharmacokinetics·2025
Human enteroid monolayers – A fit-for purpose model to elucidate intestinal natural product-drug interactions
Drug Metabolism and Pharmacokinetics·2025
Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy
Pharmacology & Therapeutics·2025
Isolation of Primary Human Proximal Tubule Epithelial Cells and Their Use in Creating a Microphysiological Model of the Renal Proximal Tubule
Journal of Visualized Experiments·2025· 3 cited
A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption
Journal of Pharmacology and Experimental Therapeutics·2025· 1 cited
Examining the Nephrotoxicity Induced by Benzalkonium Chlorides in 2D and 3D-Cultured Human Proximal Tubule Epithelial Cells (Abstract ID: 161924)
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
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Frequent Co-authors

Jonathan Himmelfarb(16), Catherine K. Yeung(11), Allan E. Rettie(8), Danny D. Shen(7), Kenneth E. Thummel(6), Mariko Nakano(6), Elijah J. Weber(5), Richard D. Palmiter(5), David L. Eaton(5), Bhagwat Prasad(5), Jashvant D. Unadkat(5), Alenka Chapron(4), Jenna L. Voellinger(4), Thomas Neumann(4), Mary F. Hébert(4), Shih‐Yu Chang(4), Brian D. Chapron(3), Dale W. Hailey(3), Thomas R. Easterling(3), Linda J. Risler(3)