Richard L. Kraus

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index3.2kcitations62works3.12yr avg
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Research Topics

Ion channel regulation and function(36), Neuroscience and Neuropharmacology Research(21), Nicotinic Acetylcholine Receptors Study(12), Cardiac electrophysiology and arrhythmias(11), Pain Mechanisms and Treatments(6)

Publications62 total

Using High‐Throughput Iridium‐Catalyzed C─H Borylations for Rapid Investigation of Heterocyclic Fragments in Discovery Chemistry
Helvetica Chimica Acta·2025
Silyl Chloroalkenyl and Alkynyl Sulfur Pentafluorides as versatile reagents to access novel fundamental SF5 building blocks
2025Open Access
Asthma Endotypes in Southwest Asia Deployment-related Asthma
American Journal of Respiratory and Critical Care Medicine·2025
Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease
American Journal of Industrial Medicine·2025· 6 citedOpen Access
Humanized NaV1.8 rats overcome cross-species potency shifts in developing novel NaV1.8 inhibitors
Neurobiology of Pain·2025· 4 citedOpen Access
Dendriform pulmonary ossification in military combat veterans: A case series
Respiratory Medicine Case Reports·2024Open Access
Analgesia and peripheral c-fiber modulation by selective Nav1.8 inhibition in rhesus
Pain·2024· 4 citedOpen Access
2-Aminopyridines as Potent and Selective Na<sub>v</sub>1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model
ACS Medicinal Chemistry Letters·2024· 3 citedOpen Access
Dendriform Pulmonary Ossification In Combat Veterans: An Emerging Link?
2024
Severe Progressive Silicosis, Autoimmune Vasculitis and Glomerulonephritis in a Young Engineered Stone Fabricator
2024
Autonomic Dysfunction Linked to Inhibition of the Na <sub>v</sub> 1.7 Sodium Channel
Circulation·2024· 16 citedOpen Access
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels
Proceedings of the National Academy of Sciences·2023· 11 citedOpen Access
Cryo-EM structure of a voltage-gated potassium channel Kv3.1 in complex with a novel potentiator reveals a new binding site suggesting the mechanism of action
Acta Crystallographica Section A Foundations and Advances·2023Open Access
Rapidly Progressive Fixed Airways Obstruction Characterized by Obliterative Bronchiolitis and Coal Macules in an Underground Coal Miner
2023· 1 cited
Unexplained dyspnea linked to mitochondrial myopathy following military deployment to Southwest Asia and Afghanistan
Physiological Reports·2023· 3 citedOpen Access
Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerve
Channels·2022· 3 citedOpen Access
New Onset Asthma in a Nuclear Submariner Following Prolonged Exposure to Poor Air Quality
2022· 1 cited
Burden of Cardiorespiratory Impairment and Depression in Western Miners
2022
Asthma Endotypes in Post-9/11 Deployment-Related Asthma
2022· 1 cited
Translational Pharmacokinetic–Pharmacodynamic Modeling of NaV1.7 Inhibitor MK-2075 to Inform Human Efficacious Dose
Frontiers in Pharmacology·2021· 7 citedOpen Access
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Frequent Co-authors

Yuxing Li(17), Jeanine Ballard(16), Scott M. Doran(14), John J. Renger(13), Victor N. Uebele(12), James C. Barrow(11), Cuyue Tang(10), Cindy E. Nuss(10), George D. Hartman(9), Thomayant Prueksaritanont(9), Thomas S. Reger(9), Susan L. Garson(9), Michelle K. Clements(9), Jörg Striessnig(8), Kenneth E. Rittle(8), Steven V. Fox(8), Vincent P. Santarelli(8), Darrell A. Henze(8), Zhi-Qiang Yang(7), Yuhsin Kuo(7)