David A. Boltz

IIT Research Institute — United States

Medicine · Health Sciences

23h-index2.7kcitations45works2.52yr avg
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Research Topics

Influenza Virus Research Studies(24), Respiratory viral infections research(14), Immune Response and Inflammation(8), Animal Virus Infections Studies(8), Animal Disease Management and Epidemiology(7)

Publications45 total

Intranasal M2SR and BM2SR Vaccine Viruses Do Not Shed or Transmit in Ferrets
Vaccines·2024· 1 citedOpen Access
Predicting Efficacy of a Purified Inactivated Zika Virus Vaccine in Flavivirus-Naïve Humans Using an Immunological Correlate of Protection in Non-Human Primates
Microorganisms·2024· 4 citedOpen Access
Enisamium Inhibits SARS-CoV-2 RNA Synthesis
Biomedicines·2021· 6 citedOpen Access
Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy
Proceedings of the National Academy of Sciences·2021· 142 citedOpen Access
Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity
Antimicrobial Agents and Chemotherapy·2021· 21 citedOpen Access
Enisamium is an inhibitor of the SARS-CoV-2 RNA polymerase and shows improvement of recovery in COVID-19 patients in an interim analysis of a clinical trial
2021· 8 citedOpen Access
Enisamium reduces influenza virus shedding and improves patient recovery by inhibiting viral RNA polymerase activity
2020· 2 citedOpen Access
Increased vaccine tolerability and protection via NF-κB modulation
Science Advances·2020· 38 citedOpen Access
Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
PLoS ONE·2019· 27 citedOpen Access
Immune potentiator for increased safety and improved protection of vaccines by NF-kB modulation
2018Open Access
1970. Phase 1 Clinical Trial of Intranasal Immunization with M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR): Safety and Immune Response in Adults
Open Forum Infectious Diseases·2018· 1 citedOpen Access
Novel influenza vaccine M2SR protects against drifted H1N1 and H3N2 influenza virus challenge in ferrets with pre-existing immunity
Vaccine·2018· 31 citedOpen Access
Activity of enisamium, an isonicotinic acid derivative, against influenza viruses in differentiated normal human bronchial epithelial cells
Antiviral chemistry & chemotherapy·2018· 23 citedOpen Access
Antiviral effect of a derivative of isonicotinic acid enisamium iodide (FAV00A) against influenza virus
Acta Virologica·2018· 14 citedOpen Access
M2SR, a novel live influenza vaccine, protects mice and ferrets against highly pathogenic avian influenza
Vaccine·2017· 31 citedOpen Access
Development of models for Zika virus infection in mice and Rhesus macaques using a contemporary virus strain
International Journal of Infectious Diseases·2016Open Access
Selection of DNA aptamers that bind to influenza A viruses with high affinity and broad subtype specificity
Biochemical and Biophysical Research Communications·2013· 106 citedOpen Access
Vaccination against Influenza with Recombinant Hemagglutinin Expressed by Schizochytrium sp. Confers Protective Immunity
PLoS ONE·2013· 51 citedOpen Access
Inflammatory Effects of Highly Pathogenic H5N1 Influenza Virus Infection in the CNS of Mice
Journal of Neuroscience·2012· 118 citedOpen Access
No evidence of a link between influenza vaccines and Guillain–Barre syndrome–associated antiganglioside antibodies
Influenza and Other Respiratory Viruses·2011· 19 citedOpen Access
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Frequent Co-authors

Robert G. Webster(17), Elena A. Govorkova(9), Victor Margitich(6), Richard J. Smeyne(5), Richard J. Webby(5), Janice M. Bahr(5), Natalia A. Ilyushina(4), Masaaki Nakai(4), Yasuko Hatta(4), Pamuk Bilsel(4), David Bunick(4), Gail Scherba(4), Miguel Muzzio(4), Aartjan J.W. te Velthuis(4), Haeman Jang(3), Jerry R. Aldridge(3), Patrick Seiler(3), Bounlom Douangngeun(3), Settha Sinthasak(3), Phouvong Phommachanh(3)