Carlos Benitéz‐Buelga

Science for Life Laboratory — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index923citations43works2.02yr avg
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Research Topics

DNA Repair Mechanisms(24), Telomeres, Telomerase, and Senescence(12), CRISPR and Genetic Engineering(7), Mitochondrial Function and Pathology(6), Cancer therapeutics and mechanisms(5)

Publications43 total

Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
RSC Chemical Biology·2025Open Access
Modulation of OGG1 enzymatic activity by the cellular machinery – have all the boxes been ticked?
DNA repair·2025· 2 citedOpen Access
Author response for "Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1"
2025
Functional and structural impact of novel SERPINA1 variants on Alpha-1 Antitrypsin Deficiency
2025Open Access
Author response for "Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1"
2025
Identification of genetic modifying factors of lung disease in PI*ZZ Alpha-1 Antitrypsin Deficiency and their role in alveolar cells
2025
Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
2025· 2 citedOpen Access
DUSP1 and SOX2 expression determine squamous cell carcinoma of the salivary gland progression
Scientific Reports·2024· 5 citedOpen Access
Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
2024· 2 citedOpen Access
Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells
Communications Biology·2024· 9 citedOpen Access
Clinical mutations in the <i>TERT</i> and <i>TERC</i> genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity
Human Molecular Genetics·2024· 2 citedOpen Access
Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
2023· 1 citedOpen Access
Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1
2023· 2 citedOpen Access
Supplementary Data from NEIL3 Prevents Senescence in Hepatocellular Carcinoma by Repairing Oxidative Lesions at Telomeres during Mitosis
2023Open Access
Supplementary Data from NEIL3 Prevents Senescence in Hepatocellular Carcinoma by Repairing Oxidative Lesions at Telomeres during Mitosis
2023Open Access
Data from NEIL3 Prevents Senescence in Hepatocellular Carcinoma by Repairing Oxidative Lesions at Telomeres during Mitosis
2023Open Access
Data from NEIL3 Prevents Senescence in Hepatocellular Carcinoma by Repairing Oxidative Lesions at Telomeres during Mitosis
2023Open Access
Front Cover: Optimization of <i>N</i>‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1 (ChemMedChem 1/2023)
ChemMedChem·2023Open Access
Optimization of <i>N</i> ‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1
ChemMedChem·2022· 9 citedOpen Access
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies
Clinical and Translational Medicine·2022· 11 citedOpen Access
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Frequent Co-authors

Thomas Helleday(28), Olov Wallner(18), Maurice Michel(18), Ulrika Warpman Berglund(15), Evert Homan(14), Martin Scobie(14), Pål Stenmark(14), Elisée Wiita(13), Torkild Visnes(12), Ann‐Sofie Jemth(11), Kumar Sanjiv(11), Javier Benı́tez(11), Emma Rose Scaletti(11), Florian Ortis(11), Olga Loseva(10), Ana Osório(10), Helge Gad(10), Christina Kalderén(8), Rosario Perona(8), Emily C. Hank(8)