Michael P. Bova

University of Virginia — United States

Medicine · Health Sciences

25h-index3.3kcitations57works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(13), Computational Drug Discovery Methods(11), Heat shock proteins research(9), Cholinesterase and Neurodegenerative Diseases(9), Connexins and lens biology(7)

Publications57 total

Delayed onset neurologic deterioration following traumatic brain injury
Medicine Case Reports and Study Protocols·2021Open Access
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
Scientific Reports·2019· 26 citedOpen Access
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.
2019Open Access
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
2019· 2 citedOpen Access
Have outcomes improved in trauma patients age 90 years and older over the past decade: Experience at a level II trauma center
The American Journal of Surgery·2018· 2 cited
Texture induced grain coarsening in severe plastic deformed low carbon steel
Scripta Materialia·2014· 14 cited
In vitro skeletal myofiber disassembly and recovery with cardiotoxin (731.9)
The FASEB Journal·2014· 1 cited
Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
PLoS ONE·2014· 151 citedOpen Access
Thermodynamic and kinetic characterization of hydroxyethylamine β-secretase-1 inhibitors
Biochemical and Biophysical Research Communications·2013· 6 cited
Correction: Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target
PLoS ONE·2013Open Access
Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target
PLoS ONE·2013· 19 citedOpen Access
Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain
ChemMedChem·2013· 47 cited
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
Nature Communications·2013· 365 citedOpen Access
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Prime side chromane-containing inhibitors
Bioorganic & Medicinal Chemistry Letters·2013· 14 citedOpen Access
Discovery of (<i>R</i>)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND006) and (<i>R</i>)-4-Cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2<i>H</i>-pyrazolo[4,3-<i>c</i>]quinoline (ELND007): Metabolically Stable γ-Secretase Inhibitors that Selectively Inhibit the Production of Amyloid-β over Notch
Journal of Medicinal Chemistry·2013· 32 cited
Development of a Novel β-Secretase Binding Assay Using the AlphaScreen Platform
SLAS DISCOVERY·2013· 7 citedOpen Access
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2013· 21 citedOpen Access
The Medium, the Mystic, and the Physicist: Toward a General Theory of the Paranormal by Lawrence LeShan
SHILAP Revista de lepidopterología·2013Open Access
Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors
Bioorganic & Medicinal Chemistry Letters·2013· 29 citedOpen Access
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates
Bioorganic & Medicinal Chemistry Letters·2013· 11 citedOpen Access
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Frequent Co-authors

Andrei W. Konradi(18), Hing L. Sham(16), John‐Michael Sauer(15), Lany Ruslim(13), Gary D. Probst(13), Roy K. Hom(13), Anh P. Truong(12), Erich Goldbach(11), Simeon Bowers(11), Guriqbal S. Basi(10), Elizabeth Brigham(10), Michael S. Dappen(10), Ying‐zi Xu(10), Lan K. Nguyen(9), Ted Yednock(9), Danielle L. Aubele(9), Albert W. Garofalo(9), Kevin P. Quinn(9), Dean R. Artis(9), Danny Tam(8)