Dean R. Artis

Annexon Biosciences (United States) — United States

Computer Science · Physical Sciences

25h-index5.7kcitations56works2.92yr avg
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Research Topics

Computational Drug Discovery Methods(9), Monoclonal and Polyclonal Antibodies Research(8), Biochemical Analysis and Sensing Techniques(8), Chemical Synthesis and Analysis(7), Melanoma and MAPK Pathways(7)

Publications56 total

Author response: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
Efficacy and Safety of Targeted Immunotherapy with ANX005 in Treating Guillain-Barré Syndrome: A Phase 3 Multicenter Study (PL5.006)
Neurology·2025· 5 cited
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2025· 1 citedOpen Access
Results From a Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of <scp>ANX005</scp>, a C1q Inhibitor, in Patients With Guillain–Barré Syndrome
Journal of the Peripheral Nervous System·2025· 10 citedOpen Access
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025Open Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2025· 1 citedOpen Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024· 2 citedOpen Access
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
eLife·2024· 10 citedOpen Access
Author response: High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
2024Open Access
Classical Complement Activation in Lupus Nephritis Correlates with Disease Biomarkers: Results from Two Observational Studies
Journal of the American Society of Nephrology·2023
Results of Single-Arm, Phase 1b Study of Anti-C1q Treatment (ANX009) Show that the Classical Pathway Is a Key Driver of Complement Activation and Consumption in Patients with Active Lupus Nephritis
Journal of the American Society of Nephrology·2023
Including Explicit Water Molecules as Part of the Protein Structure in MM/PBSA Calculations
Journal of Chemical Information and Modeling·2013· 41 cited
Thermodynamic and kinetic characterization of hydroxyethylamine β-secretase-1 inhibitors
Biochemical and Biophysical Research Communications·2013· 6 cited
Correction: Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target
PLoS ONE·2013Open Access
Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain
ChemMedChem·2013· 47 cited
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Prime side chromane-containing inhibitors
Bioorganic & Medicinal Chemistry Letters·2013· 14 citedOpen Access
Development of a Novel β-Secretase Binding Assay Using the AlphaScreen Platform
SLAS DISCOVERY·2013· 7 citedOpen Access
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2013· 21 citedOpen Access
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor
Proceedings of the National Academy of Sciences·2013· 95 citedOpen Access
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Frequent Co-authors

Roy K. Hom(12), Hing L. Sham(12), Nanhua Yao(11), Andrei W. Konradi(11), Simeon Bowers(10), Michael P. Bova(10), Lany Ruslim(10), Ted Yednock(10), Hu Pan(9), Zhao Ren(9), Gary D. Probst(9), Anh P. Truong(8), Prabha N. Ibrahim(7), Kam Y. J. Zhang(7), Paul Beroza(7), Kevin P. Quinn(7), John‐Michael Sauer(7), Gideon Bollag(6), R. Jeffrey Neitz(6), Jennifer M. Sealy(6)