Michael D. Stern

National Institute on Aging — United States

Medicine · Health Sciences

62h-index12.7kcitations220works0.62yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(122), Ion channel regulation and function(84), Neuroscience and Neural Engineering(66), Neuroscience and Neuropharmacology Research(21), Mitochondrial Function and Pathology(12)

Publications220 total

BPS2026 - Sarcoplasmic reticulum provides memory in cardiac pacemaker cells
Biophysical Journal·2026
BPS2026 – Amplification of stochastic resonance in cardiac pacemaker cells via coupling of intracellular calcium signals to membrane voltage
Biophysical Journal·2026
A New Fight-or-Flight Pacemaker Mechanism via Ryanodine Receptor Abundance and Superclustering
2025Open Access
There are more things in heaven and Earth than we dream of in our physiology
The Journal of Physiology·2025· 1 citedOpen Access
BPS2025 - Cell stochastic resonance and memory: New mechanisms underlying complex pacemaker function
Biophysical Journal·2025
Cardiac Pacemaker Cells Harness Stochastic Resonance to Ensure Fail-Safe Operation at Low Rates Bordering on Sinus Arrest
2024· 1 citedOpen Access
Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
Cells·2024· 2 citedOpen Access
Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells
2024· 1 citedOpen Access
Stochastic resonance ensures fail-safe operation of cardiac pacemaker at low rates
Biophysical Journal·2024· 1 cited
A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure of the sinoatrial node
Biophysical Journal·2024
A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure of the sinoatrial node
Frontiers in Physiology·2023· 8 citedOpen Access
Elementary intracellular Ca signals approximated as a transition of release channel system from a metastable state
Journal of Applied Physics·2023· 5 citedOpen Access
A novel conceptual model of heart rate autonomic modulation based on a small-world modular structure and heterogeneous innervation of the sinoatrial node
2023Open Access
Super-resolved SIM imaging revealed hierarchical organization of the ryanodine receptor network in 3 dimensions in rabbit sinoatrial node cells
Biophysical Journal·2023Open Access
Synchronization of pacemaker cell firing underlies autonomic modulation of beating intervals and their variability in a numerical model of heterogeneous SA node tissue
Biophysical Journal·2023Open Access
Sinoatrial node cells and tissue operate via stochastic resonance
Biophysical Journal·2023· 1 cited
The paradigm shift: Heartbeat initiation without “the pacemaker cell”
Frontiers in Physiology·2022· 6 citedOpen Access
The paradigm shift: heartbeat initiation without “the pacemaker cell”
2022· 1 citedOpen Access
Disorder in Ca2+ release unit locations confers robustness but cuts flexibility of heart pacemaking
The Journal of General Physiology·2022· 11 citedOpen Access
Functional Heterogeneity of Cell Populations Increases Robustness of Pacemaker Function in a Numerical Model of the Sinoatrial Node Tissue
Frontiers in Physiology·2022· 17 citedOpen Access
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Frequent Co-authors

Edward G. Lakatta(26), Howard S. Silverman(12), Heping Cheng(9), Eduardo Rı́os(7), Victor A. Maltsev(6), Tatiana M. Vinogradova(5), Harold A. Spurgeon(5), Long‐Sheng Song(4), H. Miyata(4), Robert Stern(3), Alexey E. Lyashkov(3), Richard G. Hansford(3), Steven J. Sollott(3), James S.K. Sham(3), Kenneth R. Boheler(3), M. C. Capogrossi(3), Mark C. Haigney(3), M. C. Capogrossi(3), K. Yu. Bogdanov(3), Peter Bowen(2)