Alexey E. Lyashkov

National Institutes of Health — United States

Medicine · Health Sciences

30h-index3.2kcitations87works13.82yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(50), Ion channel regulation and function(27), Neuroscience and Neural Engineering(20), Mitochondrial Function and Pathology(14), Receptor Mechanisms and Signaling(14)

Publications87 total

Understanding the mechanisms linking GDF15 to dementia risk: A translational approach
Alzheimer s & Dementia·2025Open Access
Failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging
GeroScience·2025Open Access
Plasma GDF15 affects long-term dementia risk and alters neuro-immune signaling
2025· 1 citedOpen Access
Qualitative and quantitative lipidomic profiling of cardiolipin, oxidized cardiolipin, and monolysocardiolipin from human skeletal muscle by UPLC-Orbitrap-MSn
Analytica Chimica Acta·2025
Single‐extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron‐derived EVs
Journal of Extracellular Vesicles·2024· 68 citedOpen Access
Identification of glycolytic proteins as binding partners of Bri2 BRICHOS domain
Journal of Pharmaceutical and Biomedical Analysis·2023· 2 citedOpen Access
Transcriptomic and Proteomic of Gastrocnemius Muscle in Peripheral Artery Disease
Circulation Research·2023· 39 citedOpen Access
A remarkable adaptive paradigm of heart performance and protection emerges in response to the constitutive challenge of marked cardiac-specific overexpression of adenylyl cyclase type 8
Biophysical Journal·2023· 3 cited
A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8
eLife·2022· 25 citedOpen Access
Author response: A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8
2022· 1 citedOpen Access
A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8
2022· 3 citedOpen Access
Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span
Aging Cell·2022· 21 citedOpen Access
Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians
eLife·2022· 24 citedOpen Access
Author response: Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians
2022Open Access
Phosphoprotein Phosphatase 1 but Not 2A Activity Modulates Coupled-Clock Mechanisms to Impact on Intrinsic Automaticity of Sinoatrial Nodal Pacemaker Cells
Cells·2021· 14 citedOpen Access
Unbiased Proteomics, Histochemistry, and Mitochondrial DNA Copy Number Reveal Better Mitochondrial Health in Muscle of High Functioning Octogenarians
2021· 2 cited
Ca2+ and Membrane Potential Transitions During Action Potentials Are Self-Similar to Each Other and to Variability of AP Firing Intervals Across the Broad Physiologic Range of AP Intervals During Autonomic Receptor Stimulation
Frontiers in Physiology·2021· 21 citedOpen Access
Restoration of energy homeostasis by SIRT6 extends healthy lifespan
Nature Communications·2021· 183 citedOpen Access
Skeletal muscle transcriptome in healthy aging
Nature Communications·2021· 114 citedOpen Access
Proteomics in aging research: A roadmap to clinical, translational research
Aging Cell·2021· 129 citedOpen Access
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Frequent Co-authors

Edward G. Lakatta(31), Tatiana M. Vinogradova(16), Victor A. Maltsev(15), Ceereena Ubaida‐Mohien(15), Bruce D. Ziman(14), Dongmei Yang(13), Luigi Ferrucci(13), Yevgeniya Lukyanenko(11), Yael Yaniv(11), Ruin Moaddel(9), Syevda Sirenko(7), Myriam Gorospe(7), Harold A. Spurgeon(7), Antoine Younès(7), Marta González‐Freire(6), Chee W. Chia(6), Steven J. Sollott(6), Ihor Zahanich(6), Christopher H. Morrell(6), Kirill V. Tarasov(6)