Nisha Narayan

Wellcome/MRC Cambridge Stem Cell Institute — United Kingdom

Medicine · Health Sciences

15h-index1.1kcitations33works5.22yr avg
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Research Topics

Acute Myeloid Leukemia Research(10), Hippo pathway signaling and YAP/TAZ(7), MicroRNA in disease regulation(6), Epigenetics and DNA Methylation(5), Genomics and Chromatin Dynamics(4)

Publications33 total

Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens
Nature Communications·2025Open Access
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
Nature Communications·2025· 5 citedOpen Access
Identification of Epigenetic Regulators of Fibrotic Transformation in Cardiac Fibroblasts Through Bulk and Single-Cell CRISPR Screens
2025Open Access
Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Nature·2025· 25 citedOpen Access
Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens
2025· 1 citedOpen Access
Abstract 363: Genetic or pharmacological inactivation of CREBBP sensitizes B-cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
Cancer Research·2024
Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition
2023Open Access
In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis
Nature Genetics·2023· 48 citedOpen Access
Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant haematopoiesis
2022· 1 citedOpen Access
Targeting AML at the intersection of epigenetics and signaling
Science Signaling·2022· 3 cited
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression
Nature Genetics·2021· 36 citedOpen Access
Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly
Scientific Reports·2019· 5 citedOpen Access
MicroRNA-155 expression and function in AML: An evolving paradigm
Experimental Hematology·2018· 36 citedOpen Access
Microrna-211 - a Novel Oncogene in Acute Myeloid Leukemia
Blood·2017· 1 cited
The Dose-Dependent Effects of Microrna-155 in Acute Myeloid Leukemia
Blood·2016
Letting the breaks off MYCN
Cell Death and Differentiation·2016· 2 citedOpen Access
Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia
Leukemia·2016· 59 cited
The role of microRNAs miR-155 and miR-211 in myeloid malignancies
Minerva Access (University of Melbourne)·2016
Identification and Analysis of Oncogenic Pathways in Deletion 20q Acute Myeloid Leukaemia
Blood·2014
Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice
Cell Death and Differentiation·2014· 15 citedOpen Access
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Frequent Co-authors

Brian J.P. Huntly(11), Paul G. Ekert(7), George Giotopoulos(7), Lawrence Banks(6), David Lara‐Astiaso(6), Paola Massimi(5), Torsten Groß(5), Jon Zazpe(5), Francesco P. Marchese(5), Cécile K. Lopez(5), Diego Alignani(5), Jake P. Taylor‐King(5), Nikolaus Fortelny(5), Sarah J. Horton(5), Ainhoa Goñi‐Salaverri(4), Julen Mendieta-Esteban(4), Cynthia del Valle(4), Tumas Beinortas(4), Laura Pilar Aguado‐Alvaro(4), Shuchi Agrawal‐Singh(4)