Douglas R. Green

St. Jude Children's Research Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

199h-index183.0kcitations956works5.22yr avg
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Research Topics

Cell death mechanisms and regulation(338), Autophagy in Disease and Therapy(140), Immune Cell Function and Interaction(121), Mitochondrial Function and Pathology(109), Phagocytosis and Immune Regulation(97)

Publications950 total

What does BCL-2 do? From new molecular insights to the clinical implications
Cell Death and Differentiation·2026
Dnmt3a-mutant hematopoietic stem cells generate alloreactive T cells with graft vs host disease and graft vs leukemia effects
Blood·2025
Mitochondrial metabolism controls threshold of T cell activation or ‘How to fix an old engine’? 3441
The Journal of Immunology·2025Open Access
Development of a CRISPR-Cas9 KO Screening Platform to Study MHC-II Antigen Presentation in Dendritic Cells 2282
The Journal of Immunology·2025Open Access
Caspase-8 and cFLIP maintain B Cell populations and architecture 3766
The Journal of Immunology·2025Open Access
Strong pro-tumoral immune effect mediated by a prominent interferon-stimulated gene 2695
The Journal of Immunology·2025Open Access
Caspase-1-mediated GATA1 cleavage and inflammasome activation drive myeloid bias in fanconi anemia: implications for targeted therapy 2986
The Journal of Immunology·2025Open Access
Rapid metabolic regulation of a novel arginine methylation of KCa3.1 attenuates 1 T cell exhaustion 2257
The Journal of Immunology·2025Open Access
Bim-mediated selection of efficient CD8 T cell memory following viral infection 4695
The Journal of Immunology·2025Open Access
Membrane receptors cluster phosphatidylserine to activate LC3-associated phagocytosis
Nature Cell Biology·2025· 2 citedOpen Access
Well Met: RIPK1 senses S-adenosyl methionine to ensure cell survival
Life Metabolism·2025Open Access
Early methionine availability attenuates T cell exhaustion
Nature Immunology·2025· 15 citedOpen Access
Retraction Note: Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy
Nature Microbiology·2025Open Access
Regulation of inflammatory processes by caspases
Nature Reviews Molecular Cell Biology·2025· 5 cited
Protocol for the establishment of murine orthotopic lung tumors and the assessment of contralateral pulmonal metastasis by flow cytometry
STAR Protocols·2025· 1 citedOpen Access
FLIP <sub>L</sub> permits apoptotic and inflammatory signaling and inhibits necroptosis in mice without Caspase-8 oligomerization
Proceedings of the National Academy of Sciences·2025· 4 citedOpen Access
Distinct developmental outcomes in DNA repair-deficient FANCC c.67delG mutant and FANCC−/− Mice
Cell Death and Differentiation·2025· 3 cited
BCL-B Promotes Lung Cancer Invasiveness by Direct Inhibition of BOK
Cells·2025· 1 citedOpen Access
Combining theory and usability testing to inform optimization and implementation of an online primary care depression management tool
BMC Medical Informatics and Decision Making·2025Open Access
List of contributors
Elsevier eBooks·2025
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Frequent Co-authors

Lorenzo Galluzzi(9), Guido Kroemer(9), Jerry E. Chipuk(7), Eric H. Baehrecke(6), Sharad Kumar(6), Séamus J. Martin(6), Frank Madeo(5), Donald D. Newmeyer(5), Tomomi Kuwana(5), John Abrams(4), Emad S. Alnemri(4), Mikhail V. Blagosklonny(4), Francesco Cecconi(4), Wafik S. El‐Deiry(4), Gian María Fimia(4), Simone Fulda(4), Michael O. Hengartner(4), Beth Levine(4), Andreas Linkermann(4), Stuart A. Lipton(4)