Christina S. Henderson

C4 Therapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

4h-index77citations10works3.02yr avg
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Research Topics

Protein Degradation and Inhibitors(5), Cannabis and Cannabinoid Research(3), Forensic Toxicology and Drug Analysis(3), Multiple Myeloma Research and Treatments(2), Ubiquitin and proteasome pathways(2)

Publications10 total

Discovery of CFT8634, a Potent, Selective, and Orally Bioavailable Heterobifunctional Degrader of BRD9
Journal of Medicinal Chemistry·2025· 3 cited
Mdma and Methamphetamine: An Investigation of a Neurochemical and Behavioral Cross-Tolerance in the Rat
Scholarworks (University of Massachusetts Amherst)·2023Open Access
Abstract ND13: The discovery and characterization of CFT7455: A potent and selective degrader of IKZF1/3 for the treatment of relapsed/refractory multiple myeloma
Cancer Research·2022· 3 cited
Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers
Cancer Research·2022· 37 cited
Abstract LB007: CFT7455: A novel, IKZF1/3 degrader that demonstrates potent tumor regression in IMiD-resistant multiple myeloma (MM) xenograft models
Cancer Research·2021· 7 cited
CFT7455: A NOVEL, IKZF1/3 DEGRADER THAT DEMONSTRATES POTENT TUMOR REGRESSION IN A SPECTRUM OF NHL XENOGRAFT MODELS
Hematological Oncology·2021· 5 cited
Development of an AchillesTAG degradation system and its application to control CAR-T activity
Current Research in Chemical Biology·2021· 20 citedOpen Access
Adolescent MDMA Exposure Diminishes the Physiological, Behavioral, and Neurotoxic Consequences of a Subsequent Methamphetamine Binge
Journal of Drug and Alcohol Research·2014
Adolescent MDMA exposure diminishes the physiological and neurotoxic consequences of an MDMA binge in female rats
Developmental Psychobiology·2013· 2 cited
Do the neuroprotective effects of adolescent MDMA pretreatment on a subsequent MDMA binge generalize to methamphetamine?
Neurotoxicology and Teratology·2009

Frequent Co-authors

Roman V. Agafonov(6), Prasoon Chaturvedi(6), Scott J. Eron(6), Christopher G. Nasveschuk(6), Stewart L. Fisher(6), Roy M. Pollock(5), Adam Crystal(5), Andrew C. Good(4), Ashley Hart(4), Marta Isasa(4), Michelle Mahler(4), Andrew J. Phillips(4), James A. Henderson(4), David A. Proia(4), David Cocozziello(3), Ruth Kirby(3), Gesine K. Veits(3), Rhamy Zeid(3), Brendon Ladd(3), Bradley Class(3)