Randolph Alonso

Instituto Venezolano de Investigaciones Científicas — VE

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index196citations19works0.02yr avg
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Research Topics

Biological Activity of Diterpenoids and Biflavonoids(6), Traditional and Medicinal Uses of Annonaceae(5), Marine Sponges and Natural Products(4), Sesquiterpenes and Asteraceae Studies(4), Synthetic Organic Chemistry Methods(4)

Publications19 total

Synthetic diterpene derivatives from kaura-9(11),16-dien-19-oic acid: Cytostatic and cytotoxic activity against human cancer cell lines
Pharmaceutical Chemistry Journal·2006· 2 cited
Cytostatic and Cytotoxic Activity of Synthetic Diterpene Derivatives Obtained from (-)-Kaur-9(11), 16-Dien-19-Oic Acid Against Human Cancer Cell Lines
Letters in Drug Design & Discovery·2005· 10 cited
Synthesis of Trinorditerpenoid Derivatives and Evaluation of Antimicrobial and Cytotoxic Activity
Chemistry of Natural Compounds·2005· 1 cited
Synthesis of (+)‐Coronarin E, (‐)‐7‐epi‐Coronarin A and (+)‐15, 16‐Epoxy‐8(17), 13(16), 14‐Labdatriene from (+)‐Manool.
ChemInform·2004
Facile Access to Optically Active Labdane-Type Diterpenes from (+)-Manool. Synthesis of (+)-Coronarin E, (+)-15,16-Epoxy-8(17),13(16),14-labdatriene, and (+)-Labda-8(17),13(<i>Z</i>)-diene-15,16-diol
Journal of Natural Products·2003· 35 cited
An Efficient Method for the Synthesis of (+)‐Cyclozonarone, Isozonarol Δ<sup>8,9</sup> and Isozonarone Δ<sup>8,9</sup>.
ChemInform·2003
Synthesis of (+)-Coronarin E, (-)-7-<i>epi</i>-Coronarin a and (+)-15, 16-Epoxy-8(17), 13(16), 14-Labdatriene from (+)-Manool
Journal of Chemical Research·2003· 5 cited
Highly Efficient Synthesis of the Optically Active Sesquiterpene Hydroquinone (+)‐Zonarol and the Sesquiterpene Quinone (+)‐Zonarone.
ChemInform·2003
An Efficient Method for the Synthesis of (+)-Cyclozonarone, Isozonarol Δ,<sup>8,9</sup>and Isozonarone Δ<sup>8,9</sup>
Synthetic Communications·2003· 12 cited
Highly efficient Synthesis of the Optically Active Sesquiterpene Hydroquinone (+)-Zonarol and the Sesquiterpene Quinone (+)-Zonarone
Journal of Chemical Research·2002· 10 cited
ChemInform Abstract: Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)‐Atom in the Key Hydration Step of Adenosine Deaminase.
ChemInform·2000
Untitled
Helvetica Chimica Acta·1999
Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)-Atom in the Key Hydration Step of Adenosine Deaminase
Helvetica Chimica Acta·1999· 75 cited
Conformationally Restricted Nucleosides. The Reaction of Adenosine Deaminase with Substrates Built on a Bicyclo[3.1.0]hexane Template
Nucleosides and Nucleotides·1999· 30 cited
ChemInform Abstract: Facile Access to Optically Active Ring C Aromatic Diterpene Derivatives from Manool. Highly Efficient Syntheses of (+)‐12‐Methyl‐7‐oxopodocarpa‐8,11,13‐triene‐13‐carboxylic Acid, (+)‐13‐Methyl‐7‐oxopodocarpa‐8,11,13‐triene‐12‐carboxylic Acid and (+)‐Nimbiol.
ChemInform·1998
A concise approach to the antiviral nucleoside (1R,2S,4S,5S)-1-hydroxymethyl-2-hydroxy-4-(6-amino-9-purinyl)bicyclo[3.1.0]hexane
1998
Facile access to optically active ring C aromatic diterpene derivatives from manool. Highly efficient syntheses of (+)-12-methyl-7-oxo-podocarpa-8,11,13-triene-13-carboxylic acid, (+)-13-methyl-7-oxopodocarpa-8,11,13-triene-12-carboxylic acid and (+)-nimbiol
Journal of the Chemical Society Perkin Transactions 1·1998· 9 cited
ChemInform Abstract: A Facile Access to Optically Active Ring C Aromatic Diterpene Derivatives. Highly Efficient Synthesis of (+)‐12‐Methyl‐7‐ oxopodocarpa‐8,11,13‐triene‐13‐carboxylic Acid and (+)‐13‐Methyl‐7‐ oxopodocarpa‐8,11,13‐triene‐12‐carboxylic Acid from Manool.
ChemInform·1995
A facile access to optically active ring C aromatic diterpene derivatives. Highly efficient synthesis of (+)-12-methyl-7-oxopodocarpa-8,11,13-triene-13-carboxylic acid and (+)-13-methyl-7-oxopodocarpa-8,11,13-triene-12-carboxylic acid from manool
Tetrahedron Letters·1995· 7 cited

Frequent Co-authors

José E. Villamizar(7), Juan A. Fuentes(7), Eleonora Tropper(7), Víctor E. Márquez(5), Pamela Russ(4), M. Arshad Siddiqui(4), Marc C. Nicklaus(4), Harry Ford(4), Angel Orcajo(4), María Aracelis Maillo(4), A. MARTIN(4), R. A. NUNEZ(4), Clifford George(3), Fang Dai(3), Franklin Salazar(3), Susana Hernández(2), Heidi Gomis(2), Antonieta Taddei(2), Cristina Sajo(2), Tatsuhiko Nakano(2)