Pamela Russ

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.0kcitations27works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(9), HIV/AIDS drug development and treatment(8), Biochemical and Molecular Research(6), Carbohydrate Chemistry and Synthesis(5), HIV Research and Treatment(4)

Publications27 total

Synthesis and Conformational Analysis of Locked Carbocyclic Analogues of 1,3-Diazepinone Riboside, a High-Affinity Cytidine Deaminase Inhibitor
Figshare·2020Open Access
Inside Cover: North‐ and South‐Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti‐HIV Activity (ChemMedChem 8/2009)
ChemMedChem·2009Open Access
Synthesis and Conformational Analysis of Locked Carbocyclic Analogues of 1,3-Diazepinone Riboside, a High-Affinity Cytidine Deaminase Inhibitor
The Journal of Organic Chemistry·2009· 16 citedOpen Access
North‐ and South‐Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti‐HIV Activity
ChemMedChem·2009· 5 citedOpen Access
Understanding How the Herpes Thymidine Kinase Orchestrates Optimal Sugar and Nucleobase Conformations To Accommodate Its Substrate at the Active Site:  A Chemical Approach
Journal of the American Chemical Society·2005· 40 cited
Synthesis and Biological Evaluation of 5-Substituted Derivatives of the Potent Antiherpes Agent (north)-Methanocarbathymine
Journal of Medicinal Chemistry·2003· 49 citedOpen Access
Interactions of Conformationally Biased North and South 2‘-Fluoro-2‘,3‘-dideoxynucleoside 5‘-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase
Biochemistry·2000· 26 cited
Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of <i>Herpes simplex</i> Virus Type 1 Thymidine Kinase Interacting with (North)-methanocarba-thymidine<sup>,</sup>
Biochemistry·2000· 51 cited
ChemInform Abstract: Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)‐Atom in the Key Hydration Step of Adenosine Deaminase.
ChemInform·2000
Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y<sub>1</sub> Receptor Ligands
Journal of Medicinal Chemistry·2000· 129 citedOpen Access
Untitled
Helvetica Chimica Acta·1999
Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)-Atom in the Key Hydration Step of Adenosine Deaminase
Helvetica Chimica Acta·1999· 75 cited
Conformationally Restricted Nucleosides. The Reaction of Adenosine Deaminase with Substrates Built on a Bicyclo[3.1.0]hexane Template
Nucleosides and Nucleotides·1999· 30 cited
Lessons from the Pseudorotational Cycle: Conformationally Rigid AZT Carbocyclic Nucleosides and Their Interaction with Reverse Transcriptase
Nucleosides and Nucleotides·1998· 14 cited
HIV-1 Reverse Transcriptase Can Discriminate between Two Conformationally Locked Carbocyclic AZT Triphosphate Analogues
Journal of the American Chemical Society·1998· 161 cited
(1<i>S</i>,2<i>R</i>)-[(Benzyloxy)methyl]cyclopent-3-enol. A Versatile Synthon for the Preparation of 4‘,1‘a-Methano- and 1‘,1‘a-Methanocarbocyclic Nucleosides
The Journal of Organic Chemistry·1997· 51 cited
Conformational Analysis of Nucleosides Constructed on a Bicyclo[3.1.0]hexane Template. Structure-Antiviral Activity Analysis for the Northern and Southern Hemispheres of the Pseudorotational Cycle
Nucleosides and Nucleotides·1997· 13 cited
Hydroxyl- versus amide-directed cyclopropanation from the allylic position in 1-hydroxy-4-N-acyl-cyclopentenes under modified Simmons-Smith conditions
Tetrahedron Letters·1997· 15 cited
Nucleosides with a Twist. Can Fixed Forms of Sugar Ring Pucker Influence Biological Activity in Nucleosides and Oligonucleotides?
Journal of Medicinal Chemistry·1996· 247 cited
Glycosylation of the active sequence ser-ile-lys-val-ala-val from the α1 chain of laminin reduces tumor cell attachment activity
Bioorganic & Medicinal Chemistry Letters·1995· 3 cited
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Frequent Co-authors

Víctor E. Márquez(21), M. Arshad Siddiqui(10), Harry Ford(7), Clifford George(7), Abdallah Ezzitouni(6), Joseph J. Barchi(5), Marc C. Nicklaus(5), Randolph Alonso(4), Hiroaki Mitsuya(3), Fang Dai(3), James A. Kelley(3), Ron J. Feldman(2), Susana Hernández(2), Gerd Folkers(2), Léonardo Scapozza(2), Terrence R. Burke(2), Olaf R. Ludek(2), Gottfried K. Schroeder(2), Chenzhong Liao(2), Richard Wolfenden(2)