Laurent Pangon

Garvan Institute of Medical Research — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.0kcitations27works0.02yr avg
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Research Topics

DNA Repair Mechanisms(8), Epigenetics and DNA Methylation(5), Wnt/β-catenin signaling in development and cancer(5), Genetic factors in colorectal cancer(5), Cancer-related gene regulation(5)

Publications27 total

‘MCC’ protein interacts with E-cadherin and β-catenin strengthening cell–cell adhesion of HCT116 colon cancer cells
Oncogene·2017· 30 cited
JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer
Oncogene·2015· 26 cited
Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform
International Journal of Molecular Sciences·2015· 4 citedOpen Access
HIF1α deficiency reduces colon inflammation in a mouse model of proximal colon cancer
Disease Models & Mechanisms·2015· 17 citedOpen Access
MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm
International Journal of Cancer·2014· 30 citedOpen Access
MCC (mutated in colorectal cancers)
Atlas of Genetics and Cytogenetics in Oncology and Haematology·2014Open Access
Loss of special <scp>AT</scp>‐rich sequence‐binding protein 1 (<scp>SATB</scp>1) predicts poor survival in patients with colorectal cancer
Histopathology·2013· 35 cited
Sulindac activates NF-κB signaling in colon cancer cells
Cell Communication and Signaling·2013· 27 citedOpen Access
Neuropeptide Y1 Receptor in Immune Cells Regulates Inflammation and Insulin Resistance Associated With Diet-Induced Obesity
Diabetes·2012· 41 citedOpen Access
Loss of heterozygosity of the Mutated in Colorectal Cancer gene is not associated with promoter methylation in non-small cell lung cancer
Lung Cancer·2012· 5 cited
The PDZ-binding motif of MCC is phosphorylated at position −1 and controls lamellipodia formation in colon epithelial cells
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2012· 26 cited
Mutated in colorectal cancer protein modulates the NFκB pathway.
PubMed·2012· 20 cited
Loss of Special AT-Rich Binding Protein 1 Expression is a Marker of Poor Survival in Lung Cancer
Journal of Thoracic Oncology·2011· 80 citedOpen Access
Loss of expression of the chromatin remodelling protein SATB1 in lung cancer is an independent prognostic marker
Pathology·2011
The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint
Genes & Cancer·2010· 25 citedOpen Access
New regulators of the BRCA1 response to genotoxic stress
Breast Cancer Research·2010· 2 citedOpen Access
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
Nature·2009· 424 cited
Lack of Y1 signalling in immune cells leads to increased inflammation and insulin resistance
Neuropeptides·2009
Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity
Research Portal (King's College London)·2007
Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity?
British Journal of Cancer·2007· 39 citedOpen Access
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Frequent Co-authors

Maija R.J. Kohonen‐Corish(14), Zoe Docherty(8), Ian Kesterton(8), Joanna R. Morris(7), Sam Al‐Sohaily(7), Richard S. Camplejohn(7), Nicola Currey(7), Ellen Solomon(6), Dessislava Mladenova(6), Julian Barwell(6), Christina Selinger(5), Shirley Hodgson(5), Fahad Benthani(5), Caroline Langman(4), Rosalind A. Eeles(4), Phuong Tran(4), Irvin Ng(4), Elizabeth A. Musgrove(4), R Gilchrist(4), Chris Boutell(3)