David Kokel

University of California, San Francisco — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index3.7kcitations39works4.52yr avg
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Research Topics

Zebrafish Biomedical Research Applications(19), Receptor Mechanisms and Signaling(16), Neurobiology and Insect Physiology Research(8), Computational Drug Discovery Methods(5), Genetics, Aging, and Longevity in Model Organisms(5)

Publications39 total

Behavioral Profiling in Zebrafish Identifies Insecticide-Related Compounds
Journal of Agricultural and Food Chemistry·2025Open Access
Deep phenotypic profiling of neuroactive drugs in larval zebrafish
Nature Communications·2024· 15 citedOpen Access
A Multimodal, In Vivo Approach for Assessing Structurally and Phenotypically Related Neuroactive Molecules
ACS Chemical Neuroscience·2024· 2 citedOpen Access
Deep phenotypic profiling of neuroactive drugs in larval zebrafish
2024· 1 citedOpen Access
Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration
Nature Communications·2021· 38 citedOpen Access
A non-hallucinogenic psychedelic analogue with therapeutic potential
Nature·2020· 436 citedOpen Access
Chemical informatics and target identification in a zebrafish phenotypic screen
UNC Libraries·2020Open Access
Photochemical activation of TRPA1 channels in neurons and animals
UNC Libraries·2020Open Access
Identification of compounds producing non-visual photosensation via TRPA1 in zebrafish
2020· 4 citedOpen Access
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds
UNC Libraries·2020Open Access
Sigma-1 receptor ligands control a switch between passive and active threat responses
UNC Libraries·2020Open Access
Identification of Psychoplastogenic <i>N</i>,<i>N</i>-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure–Activity Relationship Studies
Journal of Medicinal Chemistry·2020· 86 citedOpen Access
Simultaneous analysis of neuroactive compounds in zebrafish
2020· 13 citedOpen Access
Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation
Nature Communications·2019· 56 citedOpen Access
Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration
2019· 1 citedOpen Access
Zebrafish behavioral profiling identifies ligands, targets, and neurons related to sedation and paradoxical excitation
Zenodo (CERN European Organization for Nuclear Research)·2019Open Access
Zebrafish behavioral profiling identifies ligands, targets, and neurons related to sedation and paradoxical excitation
Figshare·2019Open Access
σ1 receptor ligands control a switch between passive and active threat responses
Nature Chemical Biology·2016· 41 citedOpen Access
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds
Nature Chemical Biology·2016· 156 citedOpen Access
Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology
ACS Chemical Biology·2016· 44 citedOpen Access
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Frequent Co-authors

Randall T. Peterson(22), Jack C. Taylor(12), Michael J. Keiser(11), Matthew N. McCarroll(10), Douglas Myers-Turnbull(9), Leo Gendelev(9), Bryan L. Roth(8), Giancarlo N. Bruni(7), Chung Yan Cheung(6), Ding Xue(5), Andrew J. Rennekamp(5), Xi‐Ping Huang(5), Paul J. Lorello(4), Barbara J. Caldarone(4), Tjakko J. van Ham(4), Vincent Setola(4), Reid Kinser(4), Cole Helsell(4), Jung Ho Gong(4), Jason K. Sello(4)