Serge Ruccolo

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Materials Science · Physical Sciences

17h-index1.0kcitations107works5.12yr avg
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Research Topics

Crystallization and Solubility Studies(70), X-ray Diffraction in Crystallography(69), Crystallography and molecular interactions(10), CO2 Reduction Techniques and Catalysts(8), Radical Photochemical Reactions(6)

Publications107 total

Nickel-Catalyzed Deallylation for Sustainable Solution and Solid-Phase Peptide Synthesis
Organic Letters·2026
Homogenous Palladium-Catalyzed Dehalogenative Deuteration and Tritiation of Aryl Halides with D <sub>2</sub> /T <sub>2</sub> Gas
Journal of the American Chemical Society·2024· 16 cited
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
Organic Process Research & Development·2024· 13 cited
“Build Your Own” ADC Mimics: Identification of Nontoxic Linker/Payload Mimics for HIC-Based DAR Determination, High-Throughput Optimization, and Continuous Flow Conjugation
Organic Process Research & Development·2024· 4 cited
Electrocatalytic Reduction of Disulfide Bonds across Chemical Modalities
Organic Letters·2024· 4 cited
Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process
Organic Process Research & Development·2024· 1 cited
Electrocatalytic Reduction of Disulfide Bonds in Antibodies
2024· 2 citedOpen Access
“Build your own” ADC mimics: Identification of non-toxic linker/payload mimics for HIC-based DAR determination, high-throughput optimization, and continuous flow conjugation
2024· 3 citedOpen Access
Homogenous Palladium-Catalyzed Dehalogenative Deuteration and Tritiation of Aryl Halides with D2/T2 Gas
2024· 3 citedOpen Access
Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir
2023· 4 citedOpen Access
Author response for "&lt;b&gt;Chemoselective bond activation by unidirectional and asynchronous PCET using ketone photoredox catalysts&lt;/b&gt;"
2023
High-Throughput Determination of Stern–Volmer Quenching Constants for Common Photocatalysts and Quenchers
ACS Organic & Inorganic Au·2023· 59 citedOpen Access
High Throughput Determination of Stern Volmer Quenching Constants for Common Photocatalysts and Quenchers
2023Open Access
Chemoselective bond activation by unidirectional and asynchronous PCET using ketone photoredox catalysts
Chemical Science·2023· 4 citedOpen Access
Electrochemical Recycling of Adenosine Triphosphate in Biocatalytic Reaction Cascades
Journal of the American Chemical Society·2022· 40 cited
Electrochemical Recycling of Adenosine Triphosphate in Biocatalytic Reaction Cascades
2022· 2 citedOpen Access
Asymmetric Synthesis of Tertiary and Secondary Cyclopropyl Boronates via Cyclopropanation of Enantioenriched Alkenyl Boronic Esters
Organic Letters·2022· 18 cited
Catalytic reduction of carbon dioxide by a zinc hydride compound, [Tptm]ZnH, and conversion to the methanol level
Dalton Transactions·2022· 12 citedOpen Access
Utilizing in situ spectroscopic tools to monitor ketal deprotection processes
International Journal of Pharmaceutics·2021· 9 cited
Electrochemical Activation of Galactose Oxidase: Mechanistic Studies and Synthetic Applications
ACS Catalysis·2021· 38 cited
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Frequent Co-authors

Gerard Parkin(21), Daniel G. Nocera(9), Michael Rauch(9), Wesley Sattler(8), Yangzhong Qin(6), Marion H. Emmert(5), Ryan G. Hadt(5), David Gygi(5), Shao‐Liang Zheng(5), Alexandra C. Sun(4), Keith Mattern(4), Neil A. Strotman(4), Anna Fryszkowska(4), Yi Rong(4), Cecilia Bottecchia(4), Rodell C. Barrientos(4), Yu‐Sheng Chen(4), Rui Sun(3), Sandra A. Robaire(3), Neena Chakrabarti(3)