Grisha Pirianov

Immunology and Microbiology · Life Sciences

23h-index3.8kcitations55works0.22yr avg
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Research Topics

Immune Response and Inflammation(10), Aortic aneurysm repair treatments(8), Cell death mechanisms and regulation(6), Sphingolipid Metabolism and Signaling(5), Vitamin D Research Studies(4)

Publications54 total

Representative secondary PET micro and nanoplastics via ethylene glycol fragmentation (EGF): Physicochemical and immuno-toxicological properties
Chemical Engineering Journal Advances·2026Open Access
Author response for "Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists"
2025
Preclinical development of the TLR4 antagonist FP12 as a drug lead targeting the HMGB1/MD-2/TLR4 axis in lethal influenza infection
Innate Immunity·2025· 1 citedOpen Access
Representative secondary PET nanoplastics and monomer supramolecular aggregates via Ethylene Glycol Fragmentation (EGF): physicochemical and immuno-toxicological properties
SSRN Electronic Journal·2025Open Access
Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists
RSC Medicinal Chemistry·2025Open Access
Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity
Journal of Medicinal Chemistry·2021· 31 citedOpen Access
Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages
Innate Immunity·2021· 7 citedOpen Access
The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates <i>in vitro</i> and <i>in vivo</i> haematopoietic and non-haematopoietic vascular TLR4 signalling
Innate Immunity·2018· 12 citedOpen Access
Structure–Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists
Journal of Medicinal Chemistry·2018· 63 citedOpen Access
Abstract 486: A Novel Synthetic Glycolipid TLR4 Antagonist (FP7) Negatively Regulates in vitro and in vivo Hematopoietic and Non-Hematopoietic Vascular Toll Like Receptor 4 Signalling
Arteriosclerosis Thrombosis and Vascular Biology·2017
Increased expression of Lamin A/C correlates with regions of high wall-stress in abdominal aortic aneurysms.
Aorta·2016· 2 cited
Untitled
Aorta·2015Open Access
Increased Expression of Lamin A/C Correlate with Regions of High Wall Stress in Abdominal Aortic Aneurysms
Aorta·2015· 4 citedOpen Access
Erratum
Journal of Vascular Research·2015Open Access
A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development
Atherosclerosis·2015· 41 citedOpen Access
Specific inhibition of c-Jun N-terminal kinase delays preterm labour and reduces mortality
Reproduction·2015· 18 citedOpen Access
A novel small mimetic molecule TLR4 antagonist (IAXO-102) modulates TLR4 proinflammatory signalling and inhibits aortic aneurysms development
Atherosclerosis·2015· 1 cited
Conference Calendar
Journal of Vascular Research·2015Open Access
Pioglitazone Identifies a New Target for Aneurysm Treatment: Role of Egr1 in an Experimental Murine Model of Aortic Aneurysm
Journal of Vascular Research·2015· 14 citedOpen Access
Supplementary Material for: Pioglitazone Identifies a New Target for Aneurysm Treatment: Role of Egr1 in an Experimental Murine Model of Aortic Aneurysm
Figshare·2015Open Access
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Frequent Co-authors

Gillian Cockerill(13), Evelyn Torsney(11), Francesco Peri(10), Nicoletta Charolidi(8), Huseyin Mehmet(7), Charys Palmer(7), Kay W. Colston(6), K W Colston(5), Frank Neumann(5), Sarah Spiegel(4), Ken Laing(4), Christopher Huggins(4), Alessio Romerio(4), Amir H. Malkawi(4), Ian Loftus(4), Matt Thompson(4), Olivier Cuvillier(3), Lisa C. Edsall(3), Deanna L. Taylor(3), A. David Edwards(3)