Klaus Steinmeyer

Sanofi (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index6.9kcitations60works0.02yr avg
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Research Topics

Ion channel regulation and function(40), Cardiac electrophysiology and arrhythmias(23), Genetic Neurodegenerative Diseases(11), Neuroscience and Neuropharmacology Research(8), Ion Transport and Channel Regulation(6)

Publications60 total

Identification of a unique transcriptomic signature associated with islet amyloidosis
2022Open Access
SAR340835, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure
Journal of Pharmacology and Experimental Therapeutics·2021· 14 citedOpen Access
Activation of Adenosine Monophosphate—Activated Protein Kinase Reduces the Onset of Diet‐Induced Hepatocellular Carcinoma in Mice
Hepatology Communications·2020· 7 citedOpen Access
2492-PUB: KCNK16 Deficiency Protects Mice against High-Fat Diet-Induced Weight Gain
Diabetes·2019
Multi-omics insight into amyloidosis of islets from metabolically stratified living surgical donors
Diabetologie und Stoffwechsel·2019
The transcriptome of persistent or transient human beta cell dys- function caused by lipo-glucotoxicity correlates with the gene expres- sion signature of type 2 diabetic islets
Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles)·2019Open Access
INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters
Diabetologia·2017· 33 citedOpen Access
Transgenic pigs with green fluorescent protein-labeled pancreatic beta cells
Diabetologia·2016
The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results
EP Europace·2015· 7 citedOpen Access
Side pockets provide the basis for a new mechanism of Kv channel–specific inhibition
Nature Chemical Biology·2013· 59 citedOpen Access
Sensitization of Upper Airway Mechanoreceptors as a New Pharmacologic Principle to Treat Obstructive Sleep Apnea: Investigations with AVE0118 in Anesthetized Pigs
SLEEP·2013· 55 citedOpen Access
Altered stress stimulation of inward rectifier potassium channels in Andersen‐Tawil syndrome
The FASEB Journal·2011· 21 cited
Differential modulation of cardiac potassium channels by Grb adaptor proteins
Biochemical and Biophysical Research Communications·2009· 4 cited
In Vitro and In Vivo Effects of the Atrial Selective Antiarrhythmic Compound AVE1231
Journal of Cardiovascular Pharmacology·2007· 54 cited
Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter
Molecular Pharmacology·2007· 93 cited
Comparison of Potent Kv1.5 Potassium Channel Inhibitors Reveals the Molecular Basis for Blocking Kinetics and Binding Mode
Cellular Physiology and Biochemistry·2007· 41 cited
Electrostatic Interactions with a Potassium Ion in the Selectivity Filter
2007
Functional profiling of human atrial and ventricular gene expression
Pflügers Archiv - European Journal of Physiology·2005· 100 cited
Reprogramming of the Human Atrial Transcriptome in Permanent Atrial Fibrillation
Circulation Research·2005· 230 cited
Effects of the atrial antiarrhythmic drug AVE0118 on cardiac ion channels
Naunyn-Schmiedeberg s Archives of Pharmacology·2004· 90 cited
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Frequent Co-authors

Thomas J. Jentsch(21), Andreas Büsch(10), Niels Decher(9), Michael Pusch(7), Manuela C. Koch(6), C Lorenz(5), Guiscard Seebohm(5), Blanche Schwappach(4), Christian Johann Lerche(4), Constanze R Scherer(4), Markus Bleich(4), K. Ricker(3), Harald Jockusch(3), Andreas S. Barth(3), Sylvia Merk(3), Ludwig Zwermann(3), Mathias Gebauer(3), Martin Dugas(3), Gerhard Steinbeck(3), Andrea Brüggemann(3)