John J. Trill

GlaxoSmithKline (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index2.3kcitations38works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(6), Biochemical and Molecular Research(6), HIV/AIDS drug development and treatment(4), Protease and Inhibitor Mechanisms(4), Protein purification and stability(4)

Publications38 total

Purification and Reconstitution of Recombinant Myostatin Latent Complex
The FASEB Journal·2009
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors
Bioorganic & Medicinal Chemistry Letters·2008· 52 citedOpen Access
A High-Throughput Screen for Endothelial Lipase Using HDL as Substrate
SLAS DISCOVERY·2008· 19 citedOpen Access
Characterization of pristane‐induced arthritis, a murine model of chronic disease: Response to antirheumatic agents, expression of joint cytokines, and immunopathology
Arthritis & Rheumatism·2004· 72 cited
BacMam Recombinant Baculoviruses in G Protein?Coupled Receptor Drug Discovery
Receptors and Channels·2004· 55 cited
BacMam Recombinant Baculoviruses in G Protein–Coupled Receptor Drug Discovery
Receptors and Channels·2004· 22 cited
Selective Binding and Oligomerization of the Murine Granulocyte Colony-stimulating Factor Receptor by a Low Molecular Weight, Nonpeptidyl Ligand
Journal of Biological Chemistry·2003· 15 citedOpen Access
A bicistronic expression system for bacterial production of authentic human interleukin-18
Protein Expression and Purification·2003· 16 cited
Rapid expression of recombinant proteins in modified CHO cells using the baculovirus system
Cytotechnology·2002· 27 citedOpen Access
Eukaryotic Expression
2001
Characterization of the Glycosylation Profiles of Alzheimer's β-Secretase Protein Asp-2 Expressed in a Variety of Cell Lines
Journal of Biological Chemistry·2001· 94 citedOpen Access
Rapid Expression of Recombinant Proteins in Modified CHO Cells Using the Baculovirus System
2001· 2 cited
A G Protein-coupled Receptor for UDP-glucose
Journal of Biological Chemistry·2000· 341 citedOpen Access
Erratum: Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
Nature·1999· 3 citedOpen Access
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
Nature·1999· 788 cited
Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions
Journal of Biological Chemistry·1999· 99 citedOpen Access
The Assessment of NVQs
Journal of Computer Assisted Tomography·1996· 29 citedOpen Access
Anti-respiratory syncytial virus monoclonal antibodies show promise in the treatment and prophylaxis of viral disease
Biochemical Society Transactions·1995· 9 cited
Cloning, expression and functional characterization of type 1 and type 2 steroid 5α-reductases from Cynomolgus monkey: Comparisons with human and rat isoenzymes
The Journal of Steroid Biochemistry and Molecular Biology·1995· 85 cited
Production of monoclonal antibodies in COS and CHO cells
Current Opinion in Biotechnology·1995· 115 cited
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Frequent Co-authors

Jay A. Tischfield(11), Dean E. McNulty(6), Robert S. Ames(5), James J. Foley(5), Derk J. Bergsma(5), Nambi Aiyar(4), Rosalie Matico(4), Kyung Johanson(4), James A. Fornwald(4), Ronald J. Shebuski(4), Mitchell E. Reff(4), Henry M. Sarau(3), Shelagh Wilson(3), Allan R. Shatzman(3), Patrick McDevitt(3), James P. Noveral(3), David S. Pfarr(3), Barry A. Berkowitz(3), D. Williams(3), James F. Kane(3)