Sebastian Heer

Inspire — Switzerland

Immunology and Microbiology · Life Sciences

5h-index501citations14works2.32yr avg
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Research Topics

Immunotherapy and Immune Responses(5), Redox biology and oxidative stress(4), Immune Response and Inflammation(3), CAR-T cell therapy research(3), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(3)

Publications14 total

997 TIL-guided discovery of TCRs targeting epitopes derived from dark antigens and application to cancer immunotherapies
Regular and Young Investigator Award Abstracts·2025Open Access
Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma
Nature Immunology·2024· 7 citedOpen Access
Circulating Tumor Reactive KIR+CD8+ T cells Suppress Anti-Tumor Immunity in Patients with Melanoma
2024Open Access
High-resolution profiling of MHC II peptide presentation capacity reveals SARS-CoV-2 CD4 T cell targets and mechanisms of immune escape
Science Advances·2022· 28 citedOpen Access
KappaBle fluorescent reporter mice enable low-background single-cell detection of NF-κB transcriptional activity in vivo
Mucosal Immunology·2022· 4 citedOpen Access
KappaBle fluorescent reporter mice enable dynamic and low-background single-cell detection of NF-κB activity <i>in vivo</i>
2021· 1 citedOpen Access
Abstract LB027: Tracking and decoding the antigen specificity of peripherally derived T cells that infiltrate into solid tumors in patients treated with an autologous T cell therapy, PRIME IL-15 (RPTR-147)
Cancer Research·2021
High resolution profiling of MHC-II peptide presentation capacity, by Mammalian Epitope Display, reveals SARS-CoV-2 targets for CD4 T cells and mechanisms of immune-escape
2021· 1 citedOpen Access
The thioredoxin‐1 and glutathione/glutaredoxin‐1 systems redundantly fuel murine B‐cell development and responses
European Journal of Immunology·2019· 34 citedOpen Access
Author response for "The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses"
2019
The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation
Nature Communications·2018· 129 citedOpen Access
The role of cellular antioxidant systems in immunity
Repository for Publications and Research Data (ETH Zurich)·2015Open Access
Cover Picture: Eur. J. Immunol. 7/11
European Journal of Immunology·2011
Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis
European Journal of Immunology·2011· 297 citedOpen Access

Frequent Co-authors

Jan Kisielow(11), Manfred Köpf(9), Franz-Josef Obermair(5), Franziska Ampenberger(4), Martin F. Bachmann(4), Florian Renoux(4), Anthony J. Coyle(4), Harriet M. Kluger(4), Jonathan Muri(3), Luigi Tortola(3), Marisa Loi(3), Joanna F. Swain(3), Benjamin Y. Lu(3), David A. Hafler(3), Stefan Freigang(2), Gunther Spohn(2), Abdijapar Shamshiev(2), Martin Hersberger(2), Masayuki Yamamoto(2), Helen Thut(2)