Gunther Spohn

Medicine · Health Sciences

25h-index2.0kcitations37works0.02yr avg
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Research Topics

Helicobacter pylori-related gastroenterology studies(12), Veterinary medicine and infectious diseases(6), Galectins and Cancer Biology(5), RNA and protein synthesis mechanisms(4), Monoclonal and Polyclonal Antibodies Research(4)

Publications37 total

Abstract 7332: Investigating genes and pathways determining sensitivity or resistance to anti-L1cam ADCs in lymphomas
Cancer Research·2025
Abstract C112: L1CAM targeting antibody-based therapy as a novel approach for L1CAM  positive lymphomas
Molecular Cancer Therapeutics·2023
Abstract 5653: LCB97, an antibody drug conjugate (ADC) targeting a novel tumor antigen for the treatment of multiple solid tumors
Cancer Research·2023
Good tolerability and limited target-specific tissue distribution of an anti-L1CAM antibody administered to cynomolgus monkey indicates favorable safety profile of L1CAM-targeting therapies
Annals of Oncology·2018· 1 citedOpen Access
Endogenous polyclonal anti–IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation
Journal of Allergy and Clinical Immunology·2016· 17 citedOpen Access
Development of an Interleukin-1β Vaccine in Patients with Type 2 Diabetes
Molecular Therapy·2015· 73 citedOpen Access
Affinity and Potency of RTH258 (ESBA1008), a Novel Inhibitor of Vascular Endothelial Growth Factor A for the Treatment of Retinal Disorders
Investigative Ophthalmology & Visual Science·2015· 46 cited
Motility, Chemotaxis, and Flagella
ASM Press eBooks·2014· 52 cited
Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes
Molecular Therapy — Methods & Clinical Development·2014· 58 citedOpen Access
Antagonism of PDGFRβ Inhibits Pericyte Recruitment in a Mouse Model of Corneal Neovascularization
2013
A VLP‐based vaccine against interleukin‐1α protects mice from atherosclerosis
European Journal of Immunology·2012· 31 citedOpen Access
Cover Picture: Eur. J. Immunol. 7/11
European Journal of Immunology·2011
A Recombinant Influenza A Virus Expressing Domain III of West Nile Virus Induces Protective Immune Responses against Influenza and West Nile Virus
PLoS ONE·2011· 40 citedOpen Access
Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis
European Journal of Immunology·2011· 297 citedOpen Access
Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice
Vaccine·2010· 65 cited
A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice
Virology Journal·2010· 98 citedOpen Access
Active immunization with IL‐1 displayed on virus‐like particles protects from autoimmune arthritis
European Journal of Immunology·2008· 89 cited
Exploiting viral properties for the rational design of modern vaccines
Expert Review of Vaccines·2008· 47 cited
Transcriptional Regulation of Stress Response and Motility Functions in<i>Helicobacter pylori</i>Is Mediated by HspR and HrcA
Journal of Bacteriology·2007· 50 citedOpen Access
A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-α Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis
The Journal of Immunology·2007· 103 cited
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Frequent Co-authors

Vincenzo Scarlato(15), Martin F. Bachmann(14), Isabel Delany(12), Rino Rappuoli(9), Gary T. Jennings(7), Iris Keller(4), Abdijapar Shamshiev(3), Martin Hersberger(3), Reto Guler(3), Pål Johansen(3), Markus Beck(3), Patrik Maurer(3), Davide Roncarati(3), Alberto Danielli(3), Flavio Mehli(3), Stefan Freigang(2), Franziska Ampenberger(2), Sebastian Heer(2), Jan Kisielow(2), Masayuki Yamamoto(2)