Irina Mirkina

Vienna Consulting Engineers (Austria) — Austria

Immunology and Microbiology · Life Sciences

18h-index934citations37works0.02yr avg
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Research Topics

Mast cells and histamine(11), Asthma and respiratory diseases(4), Monoclonal and Polyclonal Antibodies Research(4), Polyamine Metabolism and Applications(4), Macrophage Migration Inhibitory Factor(4)

Publications37 total

Abstract 585: Pretargeted radioimmunotherapy with a novel anti-oxMIF/HSG bispecific antibody and a Lu177-loaded HSG radioligand results in significant tumor regression in murine models of cancer
Cancer Research·2023
Abstract 2974: Targeting the oxidized form of macrophage migration inhibitory factor (oxMIF) with antibody ON203 activates the tumor microenvironment
Cancer Research·2023· 2 cited
1059 ON203: A new antibody targeting the oxidized form of macrophage migration inhibitory factor (oxMIF) exerts antitumorigenic activity and modulates the tumor microenvironment
Regular and Young Investigator Award Abstracts·2022Open Access
Abstract 313: Novel bioengineered monoclonal antibodies targeting oxidized macrophage migration inhibitory factor as anti-cancer therapeutics and companion diagnostics
Cancer Research·2022· 1 cited
On the selection of relevant historical demand data for revenue management applied to transportation
Journal of Revenue and Pricing Management·2022· 1 citedOpen Access
Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in<i>in vitro</i>and<i>in vivo</i>lung infection models using monoclonal antibodies
Virulence·2018· 17 citedOpen Access
Disarming <i>Staphylococcus aureus</i> from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies
Figshare·2018Open Access
Disarming <i>Staphylococcus aureus</i> from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies
Virulence·2017· 40 citedOpen Access
Multiple Modes of Action of a Monoclonal Antibody against Multidrug-Resistant Escherichia coli Sequence Type 131-<i>H</i>30
Antimicrobial Agents and Chemotherapy·2017· 19 citedOpen Access
Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against<i>Klebsiella pneumoniae</i>ST258
Virulence·2017· 48 citedOpen Access
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of<i>Staphylococcus aureus</i>for the generation of neutralizing antibodies
mAbs·2016· 48 citedOpen Access
Crystal structure of LukGH from Staphylococcus aureus in complex with a neutralising antibody
2016
Bactericidal Monoclonal Antibodies Specific to the Lipopolysaccharide O Antigen from Multidrug-Resistant Escherichia coli Clone ST131-O25b:H4 Elicit Protection in Mice
Antimicrobial Agents and Chemotherapy·2015· 34 citedOpen Access
Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of <i>Staphylococcus aureus</i> with a single human monoclonal antibody
mAbs·2014· 141 citedOpen Access
Phenotyping of Human Melanoma Cells Reveals a Unique Composition of Receptor Targets and a Subpopulation Co-Expressing ErbB4, EPO-R and NGF-R
PLoS ONE·2014· 16 citedOpen Access
5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand
Blood·2012· 38 citedOpen Access
The PI3-Kinase/mTOR-Targeting Drug NVP-BEZ235 Inhibits Growth and IgE-Dependent Activation of Human Mast Cells and Basophils
PLoS ONE·2012· 26 citedOpen Access
5-Azacytidine and Decitabine Induce FAS Re-Expression, Exert Major Proapoptotic Effects, and Cooperate with the FAS Ligand in Producing Apoptosis in Neoplastic Human Mast Cells,
Blood·2011
Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536
Haematologica·2011· 18 citedOpen Access
Phenotypic heterogeneity, novel diagnostic markers, and target expression profiles in normal and neoplastic human mast cells
Best Practice & Research Clinical Haematology·2010· 61 cited
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Frequent Co-authors

Peter Valent(12), Eszter Nagy(9), Adriana Badarau(8), Harald Herrmann(8), Lukas Stulik(7), Ivana Doležílková(6), Barbara Peter(6), Emir Hadzijusufovic(6), Harald Rouha(5), Zehra Visram(5), Barbara Maierhofer(5), Karin Groß(5), Gerhild Zauner(5), Stefan Malafa(5), Sabine Cerny‐Reiterer(5), Winfried F. Pickl(5), Gábor Nagy(4), Karina Schuch(4), Susanne Weber(4), Cecília Varga(4)