Charles Lu

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index26.6kcitations141works6.62yr avg
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Research Topics

Cancer Genomics and Diagnostics(39), RNA modifications and cancer(20), Epigenetics and DNA Methylation(16), Lung Cancer Treatments and Mutations(14), Acute Myeloid Leukemia Research(9)

Publications138 total

A genome-wide CRISPR screen identifies the TNRC18 gene locus as a regulator of inflammatory signaling
Nature Communications·2025Open Access
1039 Evaluating the prognostic impact of tebentafusp-associated cutaneous toxicities on survival in 83 uveal melanoma patients: a multi-institutional cohort study
Regular and Young Investigator Award Abstracts·2025Open Access
Genetic mapping and predictive modeling of paralog synthetic lethality
Cell Reports·2025Open Access
1110 KADANN: a generalizable kolmogorov-arnold domain adversarial neural network for robust cell annotation across diverse tumor microenvironments
Regular and Young Investigator Award Abstracts·2025Open Access
Spatial proteomics for investigating solid tumor resistance mechanisms
Cancer and Metastasis Reviews·2025· 1 cited
0379 Survival implications of systemic immunosuppression timing, dosage, and duration in immune checkpoint inhibitor therapy: A retrospective multicohort study
Journal of Investigative Dermatology·2025· 1 citedOpen Access
0080 Using large language models to identify cutaneous immune-related adverse events in response to immunotherapy
Journal of Investigative Dermatology·2025Open Access
Revisiting the Definition of Acral Melanoma: Unraveling Histology and Location
2025Open Access
Effect of systemic glucocorticoid immunosuppression timing, dose, and duration on overall survival among immune checkpoint inhibitor recipients: a retrospective multicohort study
2025Open Access
Optimization of Genome-wide CRISPR Screens using dual-guide RNA Infection with Cas9 Electroporation (DICE)
2025
SP06. Pudendal Nerve Entrapment: Efficacy of Surgical Decompression in Alleviating Pain Symptoms
Plastic & Reconstructive Surgery Global Open·2025Open Access
Synthetic lethality of mRNA quality control complexes in cancer
Nature·2025· 16 citedOpen Access
gen3DNet: An R Package for Generating 3D Network Models
2024· 1 citedOpen Access
Anti–Programmed Death Ligand 1 Plus Targeted Therapy in Anaplastic Thyroid Carcinoma
JAMA Oncology·2024· 49 citedOpen Access
Long-Term Outcomes of a Prospective Randomized Trial of Passive Scattering Proton Therapy vs. Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer
International Journal of Radiation Oncology*Biology*Physics·2024
Genetic Mapping of All Human Paralog Pairs to Characterize Synthetic Lethality and Buffering
2024
Building a translational cancer dependency map for The Cancer Genome Atlas
Nature Cancer·2024· 22 citedOpen Access
PP01.42 EGFR Germline Mutations in Lung Adenocarcinoma: A Single-Center Experience
Journal of Thoracic Oncology·2024· 1 citedOpen Access
The chromatin landscape of healthy and injured cell types in the human kidney
Nature Communications·2024· 35 citedOpen Access
Genome-scale functional genomics screening highlights genes impacting protein fucosylation in Chinese hamster ovary cells
SLAS DISCOVERY·2023· 3 citedOpen Access
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Frequent Co-authors

Richard K. Wilson(24), Elaine R. Mardis(22), Li Ding(20), Robert S. Fulton(16), James R. Downing(13), Gang Wu(12), John Easton(12), Christopher A. Miller(11), Lucinda Fulton(11), Xiang Chen(11), Jinghui Zhang(11), Michael D. McLellan(10), Joshua F. McMichael(10), Michael Rusch(10), David J. Dooling(9), Robert Huether(9), Matthew Parker(9), David W. Ellison(9), Bhavin Vadodaria(9), Sheila Shurtleff(9)