James T. Earnest

University of Central Florida — United States

Medicine · Health Sciences

16h-index2.2kcitations29works2.52yr avg
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Research Topics

Mosquito-borne diseases and control(15), Viral Infections and Vectors(11), SARS-CoV-2 and COVID-19 Research(8), Viral Infections and Outbreaks Research(5), COVID-19 Clinical Research Studies(4)

Publications29 total

TRAVEL-ASSOCIATED CHIKUNGUNYA VIRUS INFECTION, MEXICO, 2025
2026Open Access
Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases
New England Journal of Medicine·2025· 1 citedOpen Access
The TIRS trial: Enrollment procedures and baseline characterization of a pediatric cohort to quantify the epidemiologic impact of targeted indoor residual spraying on Aedes-borne viruses in Merida, Mexico
PLoS ONE·2024· 3 citedOpen Access
Evidence of Ongoing Transmission of Zika Virus in Mérida, Mexico
American Journal of Tropical Medicine and Hygiene·2024· 6 citedOpen Access
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8
Cell·2023· 36 citedOpen Access
A chikungunya virus–like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans
Science Translational Medicine·2023· 38 citedOpen Access
Human IgG antibody responses to severe acute respiratory syndrome coronavirus 2 viral antigens receptor-binding domain, spike, and nucleocapsid, in vaccinated adults from Merida, Mexico
Frontiers in Medicine·2022Open Access
SARS-CoV-2 antibody prevalence in a pediatric cohort of unvaccinated children in Mérida, Yucatán, México
PLOS Global Public Health·2022Open Access
Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses
Proceedings of the National Academy of Sciences·2021· 29 citedOpen Access
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope
Cell·2021· 78 citedOpen Access
The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies
Cell Reports·2021· 39 citedOpen Access
SARS-CoV-2 Antibody Prevalence in a Pediatric Cohort of Unvaccinated Children in Mérida, Yucatán, México
SSRN Electronic Journal·2021Open Access
LDLRAD3 is a receptor for Venezuelan equine encephalitis virus
Nature·2020· 154 citedOpen Access
Structural basis of Chikungunya virus inhibition by monoclonal antibodies
Proceedings of the National Academy of Sciences·2020· 70 citedOpen Access
Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Nature Immunology·2020· 43 citedOpen Access
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)
2020
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
2020
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
2020
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Nature Immunology·2020· 979 citedOpen Access
SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function
2020· 44 citedOpen Access
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Frequent Co-authors

Michael Diamond(15), Julie M. Fox(7), Daved H. Fremont(7), Henry Puerta‐Guardo(7), Arthur S. Kim(6), Guadalupe Ayora‐Talavera(6), Gonzalo M. Vazquez‐Prokopec(6), Emma S. Winkler(5), Natasha M. Kafai(5), Katherine Basore(5), Oscar D. Kirstein(5), Gloria Abigail Barrera-Fuentes(5), Norma Pavía‐Ruz(5), Pilar Granja-Pérez(5), Pablo Manrique‐Saide(5), Adam L. Bailey(4), Tom Gallagher(4), Thiam‐Seng Ng(4), G. Fibriansah(4), V.A. Kostyuchenko(4)