Becket Feierbach

Gilead Sciences (United States) — United States

Medicine · Health Sciences

26h-index7.1kcitations63works15.02yr avg
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Research Topics

Hepatitis B Virus Studies(40), Hepatitis C virus research(36), Liver Disease Diagnosis and Treatment(27), Herpesvirus Infections and Treatments(13), Cytomegalovirus and herpesvirus research(10)

Publications63 total

Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B
Gut·2024· 15 citedOpen Access
A gene editing approach for chronic hepatitis B: elimination of hepatitis B virus in vivo by targeting cccDNA and integrated viral genomes with a sequence-specific ARCUS nuclease
Journal of Hepatology·2023
Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells
JHEP Reports·2022· 24 citedOpen Access
Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection
Antimicrobial Agents and Chemotherapy·2022· 13 citedOpen Access
Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus
PLoS ONE·2022· 18 citedOpen Access
Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D <scp>HBeAg</scp>‐positive chronic hepatitis B
Alimentary Pharmacology & Therapeutics·2022· 5 citedOpen Access
Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System
Journal of Virology·2022· 3 citedOpen Access
Reply to: “Hepatocyte expression of hepatitis B surface and core antigens across phases of chronic hepatitis B infection”
Journal of Hepatology·2022
Long-read sequencing of HCC samples reveals complete architecture of HBV integrations and chimeric mRNA isoforms associated with oncogenes
Journal of Hepatology·2022
Quantification of HBV hepatocyte burden using novel multiplex immunofluorescence staining and image analysis reveals substantial reduction in HBV liver burden with anti-viral treatment
Journal of Hepatology·2022· 1 cited
Effect of tenofovir disoproxil fumarate treatment on intrahepatic viral burden and liver immune microenvironment in chronic hepatitis B patients with minimally elevated serum alanine aminotransferase
Journal of Hepatology·2022
Decrease in the burden of integrated hepatitis B virus DNA in chronic hepatitis B patients with minimally elevated alanine aminotransferase on tenofovir disoproxil fumarate as revealed by long-read DNA-sequencing
Journal of Hepatology·2022· 2 cited
Intrahepatic transcriptional profiling demonstrates preclinical models of chronic hepatitis B resemble different stages of natural history in humans
Journal of Hepatology·2022
Multi-omics analysis of human livers reveals variation in intrahepatic inflammation across chronic hepatitis B infection phases
Journal of Hepatology·2022· 1 cited
Characterization of a KDM5 Small Molecule Inhibitor with Antiviral Activity against Hepatitis B Virus
2022· 4 citedOpen Access
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo
Molecular Therapy·2022· 45 citedOpen Access
Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therapy
PLoS ONE·2022· 16 citedOpen Access
Multi-parametric analysis of human livers reveals variation in intrahepatic inflammation across phases of chronic hepatitis B infection
Journal of Hepatology·2022· 73 citedOpen Access
Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B
JHEP Reports·2022· 48 citedOpen Access
Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection
JHEP Reports·2021· 49 citedOpen Access
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Frequent Co-authors

Hongmei Mo(13), Nicholas van Buuren(11), Li Li(11), William E. Delaney(10), Anuj Gaggar(10), Ricardo Ramírez(9), Vithika Suri(9), Simon P. Fletcher(7), Ashley E. Fouts(6), Dara Burdette(6), Patrick Marcellin(6), Ross Martin(6), Yang Liu(6), Margaret E. Bisher(5), Lynn W. Enquist(5), Marı́a Buti(5), Lindsey May(5), Henry Lik‐Yuen Chan(5), Danny Tam(5), Abhishek Aggarwal(4)