Sophie Schobesberger

Universität Hamburg — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index705citations26works0.02yr avg
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Research Topics

Ion channel regulation and function(12), Cardiac electrophysiology and arrhythmias(9), Receptor Mechanisms and Signaling(7), Electrochemical Analysis and Applications(5), Neuroscience and Neural Engineering(5)

Publications25 total

Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.
EBioMedicine·2020· 26 citedOpen Access
β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes
eLife·2020· 38 citedOpen Access
Author response: β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes
2020Open Access
Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes
Cellular Signalling·2019· 7 cited
Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts
Cell Reports·2018· 64 citedOpen Access
In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but Not to Ca2+ Handling or β-Adrenoceptor Signaling
Anesthesiology·2018· 9 citedOpen Access
Function of L-Type Calcium Channel Microdomain in Human Myocytes from Hearts with Ischemic versus Dilated Cardiomyopathies
Biophysical Journal·2018· 1 citedOpen Access
Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity
Scientific Reports·2017· 23 citedOpen Access
beta(3) adrenergic signaling alters compartmentation and NO/cGMP/PDE2 signaling in heart failure
2017
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure
Cardiovascular Research·2017· 59 citedOpen Access
Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure
Circulation Research·2016· 113 citedOpen Access
Nanoscale, Voltage-Driven Application of Bioactive Substances onto Cells with Organized Topography
Biophysical Journal·2016· 10 citedOpen Access
Microtubule-Dependent Mitochondria Alignment Regulates Calcium Release in Response to Nanomechanical Stimulus in Heart Myocytes
Cell Reports·2015· 67 citedOpen Access
Abstract 15700: L-type Calcium Channels Localization and Function are Affected by Microdomain Remodelling in Human Failing Cardiomyocytes
Circulation·2015
Direct Evidence for Microdomain-Specific Localization and Remodeling of Functional L-Type Calcium Channels in Rat and Human Atrial Myocytes
Circulation·2015· 94 citedOpen Access
Studying GPCR/cAMP pharmacology from the perspective of cellular structure
Frontiers in Pharmacology·2015· 19 citedOpen Access
Changes in cardiomyocyte structure and cAMP/cGMP signalling during heart failure
Spiral (Imperial College London)·2015Open Access
Abstract 18709: Increased Open Probability of L-type Calcium Channels Localized in T-tubules in Patients With Chronic Atrial Fibrillation: Role of Channel Subunits
2014· 1 cited
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling
Journal of Molecular and Cellular Cardiology·2013· 114 citedOpen Access
Abstract 10467: Distinct Distribution of Functional Calcium Channels Revealed by Super-resolution Scanning Patch-clamp in Adult Rat Atrial Cardiomyocytes
Circulation·2013· 1 cited
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Frequent Co-authors

Julia Gorelik(22), Peter Wright(10), Viacheslav O. Nikolaev(10), Markus B. Sikkel(9), Jose L. Sanchez‐Alonso(9), Anamika Bhargava(7), Siân E. Harding(7), Claire Poulet(7), Sergiy Tokar(5), Alexander R. Lyon(5), Alexey V. Glukhov(5), Navneet Bhogal(5), Catherine Mansfield(5), Ivan Diakonov(4), Prakash P Punjabi(4), Giuseppe Faggian(4), Natalia A. Trayanova(3), Marina Balycheva(3), Áron Monszpart(3), Andreas Friebe(3)