Patrick Caplazi

Rutgers, The State University of New Jersey — United States

Medicine · Health Sciences

34h-index5.7kcitations81works0.22yr avg
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Research Topics

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(8), Immune Cell Function and Interaction(8), T-cell and B-cell Immunology(7), Virology and Viral Diseases(7), Cytokine Signaling Pathways and Interactions(6)

Publications80 total

Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosis
2025Open Access
Abstract 2430: Artificial intelligence enables prediction of MET amplification & associated morphologic features from H&E-stained NSCLC specimens
Cancer Research·2025
Voxel-based analysis of renal fibrosis with diffusion MRI in mouse models
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2024
Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease
American Journal of Physiology-Renal Physiology·2024· 1 cited
Abstract 905: ML quantification of tumor-Infiltrating lymphocytes distinguishes immune-phenotypes and reveals phenotypic heterogeneity
Cancer Research·2024
Integration of human stem cell-derived in vitro systems and mouse preclinical models identifies complex pathophysiologic mechanisms in retinal dystrophy
Frontiers in Cell and Developmental Biology·2023· 4 citedOpen Access
LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung
Science Advances·2023· 44 citedOpen Access
Obligate role for Rock1 and Rock2 in adult stem cell viability and function
Heliyon·2023· 6 citedOpen Access
Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Cell Reports·2023· 6 citedOpen Access
Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone
European Respiratory Journal·2022· 20 citedOpen Access
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
Cell Metabolism·2022· 46 cited
BMP1 is not required for lung fibrosis in mice
Scientific Reports·2022· 8 citedOpen Access
BMP1 is Not Required for Lung Fibrosis in Mice
Research Square (Research Square)·2021Open Access
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Science Translational Medicine·2021· 125 citedOpen Access
Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
Journal for ImmunoTherapy of Cancer·2021· 144 citedOpen Access
Abstract PO084: Patterns of T cell clonal expansion in cancer patients associate with response to immunotherapy
Cancer Immunology Research·2021
A WISP1 Antibody Inhibits MRTF Signaling to Prevent the Progression of Established Liver Fibrosis
SSRN Electronic Journal·2021Open Access
Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage
Communications Biology·2020· 15 citedOpen Access
TPL2 kinase action and control of inflammation
The Journal of Immunology·2020
Peripheral T cell expansion predicts tumour infiltration and clinical response
Nature·2020· 772 cited
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Frequent Co-authors

Wyne P. Lee(12), Zora Modrušan(10), Jason DeVoss(10), Surinder Jeet(9), Mercedesz Balázs(8), Merone Roose‐Girma(7), Ivan Peng(7), Jane L. Grogan(6), Yonglian Sun(6), F. Ehrensperger(6), Jason A. Hackney(5), Tao Sai(5), Flavius Martin(5), Søren Warming(5), Naruhisa Ota(5), Kate Senger(5), Lucinda Tam(5), Ali A. Zarrin(5), Justin Lesch(4), Wenjun Ouyang(4)