Toshie Sakuma

Soka University of America — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index1.9kcitations46works0.02yr avg
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Research Topics

Virus-based gene therapy research(8), HIV Research and Treatment(6), interferon and immune responses(6), Pancreatic function and diabetes(5), CRISPR and Genetic Engineering(5)

Publications46 total

Health, Automation, and Life: A Task-Based Model with Endogenous Mortality
SSRN Electronic Journal·2025Open Access
Can AI Fully Automate Human Work? Biological Limits from Endogenous Mortality
SSRN Electronic Journal·2025Open Access
Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
Vaccine·2022· 14 citedOpen Access
Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
2021· 2 cited
Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation
iScience·2021· 4 citedOpen Access
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses
UNC Libraries·2020Open Access
Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS)
Journal of Chemical Information and Modeling·2020· 8 citedOpen Access
Abstract CT090: Rational design of an oncolytic virus permits use of interferon beta as a pharmacodynamic marker for clinical application
Clinical Trials·2019
Abstract CT090: Rational design of an oncolytic virus permits use of interferon beta as a pharmacodynamic marker for clinical application
Cancer Research·2019
Homology Modelling of Sodium Iodide Symporter
Biophysical Journal·2018Open Access
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses
PLoS Pathogens·2015· 46 citedOpen Access
41. U2 snRNP Spliceosome Proteins Block Recombinant AAV Vector Transduction
Molecular Therapy·2015Open Access
β-Cell-targeted blockage of PD1 and CTLA4 pathways prevents development of autoimmune diabetes and acute allogeneic islets rejection
Gene Therapy·2015· 53 citedOpen Access
Beta cell regeneration after single-round immunological destruction in a mouse model
Diabetologia·2014· 26 citedOpen Access
Murine Leukemia Virus Uses TREX Components for Efficient Nuclear Export of Unspliced Viral Transcripts
Viruses·2014· 10 citedOpen Access
Murine Leukemia Virus Uses NXF1 for Nuclear Export of Spliced and Unspliced Viral Transcripts
Journal of Virology·2014· 43 citedOpen Access
Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic <i>Glp-1</i> gene therapy
Disease Models & Mechanisms·2013· 47 citedOpen Access
Intrapatient Variations in Type 1 Diabetes-specific iPS Cell Differentiation Into Insulin-producing Cells
Molecular Therapy·2012· 96 citedOpen Access
Lentiviral vectors: basic to translational
Biochemical Journal·2012· 331 cited
Pharmacometabonomics of Ginseng Extracts on Vascular Injury Induced by Chronic Homocysteine Treatment.
Planta Medica·2012
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Frequent Co-authors

Yasuhiro Ikeda(18), Seiga Ohmine(13), Tayaramma Thatava(12), Jason M. Tonne(11), Yogish C. Kudva(7), Kah-Whye Peng(7), Stephen J. Russell(6), Michael A. Barry(4), Jiro Yasuda(4), Yasuhiro Ikeda(4), Karen A. Squillace(4), Sara J. Holditch(4), Nandakumar Packiriswamy(4), Lianwen Zhang(4), Ramakrishna Edukulla(3), André Terzic(3), Michael Deeds(3), Claire A. Schreiber(3), Yoshihiro Izumiya(3), Raymond Hickey(3)