Mehrdad Shamloo

Beth Israel Deaconess Medical Center — United States

Neuroscience · Life Sciences

49h-index9.4kcitations102works12.12yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(27), Neuroscience and Neuropharmacology Research(26), Alzheimer's disease research and treatments(13), Tryptophan and brain disorders(12), Mitochondrial Function and Pathology(11)

Publications101 total

Eye‐Targeted <scp>A20</scp> Gene Therapy Alleviates Ischemic Retinopathy by Reducing Pathologic Neovascularization, Gliosis, and Neuronal Apoptosis
The FASEB Journal·2025Open Access
Age-related microbiome metabolites alter RNA splicing and chromatin accessibility in the brain
2025· 1 citedOpen Access
Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson’s disease mice
npj Parkinson s Disease·2025· 5 citedOpen Access
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease
Journal of Neuroinflammation·2024· 21 citedOpen Access
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer's disease.
2024· 2 citedOpen Access
Mapping of catecholaminergic denervation, neurodegeneration, and inflammation in 6-OHDA-treated Parkinson's disease mice
2024· 1 citedOpen Access
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
Cell·2024· 14 citedOpen Access
Impact of high-fat diet on cognitive behavior and central and systemic inflammation with aging and sex differences in mice
Brain Behavior and Immunity·2024· 53 citedOpen Access
Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease
Discover Mental Health·2023· 3 citedOpen Access
NORADRENERGIC MODULATION OF BEHAVIOR, NEUROINFLAMMATION AND PATHOLOGY IN BRAIN DISORDERS
IBRO Neuroscience Reports·2023Open Access
The anti-inflammatory effects of photobiomodulation are mediated by cytokines: Evidence from a mouse model of inflammation
Frontiers in Neuroscience·2023· 53 citedOpen Access
Schwann Cells Promote Sensory Neuron Excitability During Development
SSRN Electronic Journal·2023Open Access
Locus Coeruleus and Noradrenergic Pharmacology in Neurodegenerative Disease
Handbook of experimental pharmacology·2023· 8 cited
Protective anti-inflammatory effects of photobiomodulation with Red/NIR light in a mouse model of LPS-induced systemic and brain inflammation
Research Square (Research Square)·2022Open Access
Brain‐Wide Cellular Resolution Regional Quantification of Microglia and Amyloid in 5xFAD mice
Alzheimer s & Dementia·2022
Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration
Frontiers in Pharmacology·2022· 24 citedOpen Access
Schwann cells promote sensory neuron excitability during development
2022· 2 citedOpen Access
Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease
2022· 1 citedOpen Access
Maturation and circuit integration of transplanted human cortical organoids
Nature·2022· 438 citedOpen Access
Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis
Frontiers in Immunology·2022· 48 citedOpen Access
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Frequent Co-authors

Nay L. Saw(11), Tadeusz Wieloch(9), Karoly Nikolich(5), Erwin B. Defensor(5), Daria Mochly‐Rosen(5), Mehrdad Faizi(5), Pooneh Memar Ardestani(5), Angelo Encarnacion(4), Tony Wyss‐Coray(4), Patrick L. Bader(4), Rachel Lam(4), Bitna Yi(4), Andrew K. Evans(4), Gunilla Gidö(3), Laurence Coutellier(3), Marie Monbureau(3), Alexander M. Kleschevnikov(3), William C. Mobley(3), Amit U. Joshi(3), Mattias Rickhag(3)