Antoni Nasal

Gdańsk Medical University — Poland

Chemistry · Physical Sciences

18h-index1.3kcitations68works0.02yr avg
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Research Topics

Analytical Chemistry and Chromatography(27), Analytical Methods in Pharmaceuticals(11), Eicosanoids and Hypertension Pharmacology(9), Computational Drug Discovery Methods(8), Receptor Mechanisms and Signaling(8)

Publications68 total

Determination of the anti-inflammatory activity of fruits of some varieties of Rubus idaeus and Rubus occidentalis (Rosaceae)
Phytochemistry Letters·2025
Development of the thin film solid phase microextraction (TF-SPME) method for metabolomics profiling of steroidal hormones from urine samples using LC-QTOF/MS
Frontiers in Molecular Biosciences·2023· 18 citedOpen Access
Are Alpha-2D Adrenoceptor Subtypes Involved in Rat Mydriasis Evoked by New Imidazoline Derivatives: Marsanidine and 7-Methylmarsanidine?
Dose-Response·2017· 2 citedOpen Access
Comparative pharmacodynamic analysis of imidazoline compounds using rat model of ocular mydriasis with a test of quantitative structure–activity relationships
Journal of Pharmaceutical and Biomedical Analysis·2017· 2 cited
Hplc–MS/MS Method for Dexmedetomidine Quantification with Design of Experiments Approach: Application to Pediatric Pharmacokinetic Study
Bioanalysis·2017· 21 cited
Study on the mechanism of mydriatic activity of imidazoline derivatives dexmedetomidine, marsanidine and 7-methylmarsanidine in rats – Are alpha2D-adrenoceptors engaged?
Pharmacological Reports·2015
Metrazoline, BU224, BU226 and BU239 act on isolated rat heart atria via I2-imidazoline receptors. Are the ATP-sensitive potassium (KATP) channels also involved?
Pharmacological Reports·2015
Evaluation of pharmacological interactions of new imidazoline derivatives marsanidine and 7-methylmarsanidine with alpha2-adrenergic receptors using rat mydriasis model
Pharmacological Reports·2015
Effect of the Reference Imidazoline Drugs, Clonidine and Rilmenidine, on Rat Eye Pupil Size Confirms the Decisive Role of α2-Adrenoceptors on Mydriasis
International Journal of Pharmacology·2014· 1 citedOpen Access
The ino- and chronotropic effects of imidazoline drugs on isolated rat heart atria – are I1- imidazoline receptors involved?
Pharmacological Reports·2013
Changes of rate and force of contraction of isolated rat heart atria by imidazoline derivatives: RS 45041-190, BU224, BU239 and 2-BFI
Pharmacological Reports·2013
Application of the eye mydriasis model in rats to study on the interaction of imidazoline compounds with α2-adrenergic receptors
Pharmacological Reports·2013
Mydriasis model in rats as a simple system to evaluate α2-adrenergic activity of the imidazol(in)e compounds
Pharmacological Reports·2013· 9 cited
A new pH/organic modifier gradient RP HPLC method for convenient determination of lipophilicity and acidity of drugs as applied to established imidazoline agents
European Journal of Pharmaceutical Sciences·2012· 12 cited
Testing conception of engagement of imidazoline receptors in effects of imidazoline agents on isolated rat heart atria
Pharmacological Reports·2010
Micellar liquid chromatography for lipophilicity determination of new biologically active 1,3‐purinodiones
Journal of Separation Science·2010· 13 cited
Artificial neural networks analysis used to evaluate the molecular interactions between selected drugs and human α1-acid glycoprotein
Journal of Pharmaceutical and Biomedical Analysis·2008· 18 cited
Progress in the Use of HPLC for Evaluation of Lipophilicity
Current Computer - Aided Drug Design·2006· 29 cited
Synthesis and biological activity of tricyclic aryloimidazo-, pyrimido-, and diazepinopurinediones
Bioorganic & Medicinal Chemistry·2006· 34 cited
CCDC 289056: Experimental Crystal Structure Determination
The Cambridge Structural Database·2006Open Access
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Frequent Co-authors

Roman Kaliszan(34), Aleksandra Radwańska(13), B Damasiewicz(13), Henryk Foks(11), Adam Buciński(8), Jacek Petrusewicz(6), Piotr Haber(5), Tibor Cserháti(5), Teresa Fra̧ckowiak(5), W. KUZMIERKIEWICZ(5), R Kaliszan(4), E. Forgács(4), Michał J. Markuszewski(4), Joanna Raczak‐Gutknecht(4), Franciszek Sączewski(4), K Wisterowicz(4), Danuta Siluk(3), Paweł Wiczling(3), Piotr Kawczak(3), Janusz Grzybowski(3)