Dean Yimlamai

Yale Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index4.2kcitations36works4.42yr avg
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Research Topics

Hippo pathway signaling and YAP/TAZ(13), Liver Disease Diagnosis and Treatment(7), Lipid metabolism and biosynthesis(5), Liver physiology and pathology(4), Congenital heart defects research(3)

Publications36 total

Fetal and maternal immune cells exhibit tandem maturation across gestation and dysregulation in preterm birth
2025Open Access
Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction–associated steatohepatitis
Proceedings of the National Academy of Sciences·2025· 21 citedOpen Access
Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitis
2025· 1 citedOpen Access
292-OR: Coenzyme A Synthase Knockdown Alleviates Metabolic Dysfunction–Associated Steatohepatitis via Decreasing Cholesterol in Liver Lipid Droplets
Diabetes·2024
1571-P: CIDEB and CGI-58 Regulate Liver Lipid Droplet Size with Cholesterol Content, Linking to Inflammation and Fibrosis in Metabolic Dysfunction–Associated Steatohepatitis
Diabetes·2024
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis
Science Translational Medicine·2023· 24 citedOpen Access
In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration
Hepatology·2023· 4 citedOpen Access
Inhibition of <i>HSD17B13</i> protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis
Proceedings of the National Academy of Sciences·2023· 48 citedOpen Access
Transcriptomic profiling of a multiethnic pediatric NAFLD cohort reveals genes and pathways associated with disease
Hepatology Communications·2022· 39 citedOpen Access
Human placental villi immune cells help maintain homeostasis <i>in utero</i>
2021· 2 citedOpen Access
Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma
Journal of Clinical Investigation·2021· 139 citedOpen Access
OTME-20. Chitinase-3-like-1(CHI3L1) Protein Complexes Regulate the immunosuppressive Microenvironment in Glioblastoma
Neuro-Oncology Advances·2021Open Access
Loss of<i>Anks6</i>leads to YAP deficiency and liver abnormalities
Human Molecular Genetics·2020· 18 citedOpen Access
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice
Science Translational Medicine·2020· 113 citedOpen Access
Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity
iScience·2020· 30 citedOpen Access
The Protective Effects of Calcineurin on Pancreatitis in Mice Depend on the Cellular Source
Gastroenterology·2020· 35 citedOpen Access
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
Science Translational Medicine·2019· 113 citedOpen Access
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
2019· 6 citedOpen Access
Hepatocyte Stress Increases Expression of Yes‐Associated Protein and Transcriptional Coactivator With PDZ‐Binding Motif in Hepatocytes to Promote Parenchymal Inflammation and Fibrosis
Hepatology·2019· 150 citedOpen Access
Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth
The EMBO Journal·2018· 125 citedOpen Access
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Frequent Co-authors

Fernando D. Camargo(8), Liza Konnikova(6), Gerald I. Shulman(6), Giorgio Giacomo Galli(5), Andrew G. Cox(5), Wolfram Goessling(5), Brendan H. Fowl(5), Matthew L. Steinhauser(5), Ikki Sakuma(5), Rafael Calais Gaspar(5), Ali Nasiri(5), Mario Kahn(5), Kitt Falk Petersen(5), Daniel G. Jay(4), Katie L. Hwang(4), Kristin Brown(4), Sagar Chhangawala(4), Evan C. Lien(4), John M. Asara(4), Yariv Houvras(4)